Complete Mutation Screening and Haplotype Characterization of the BRCA1 Gene in 61 Familial Breast Cancer Patients from Norway

Mutations in the Breast-Cancer-1 (BRCA1) gene are the major cause of familial breast/ovarian cancer. Among familial breast cancer only, 15–20% have been suggested to have a deleterious mutation in BRCA1. A highly sensitive method (REF-SSCP) was applied to screen the open reading frame and the 5(’)UT...

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Detalles Bibliográficos
Autores principales: Frost, Petter, Jugessur, Astanand, Apold, Jaran, Heimdal, Ketil, Aloysius, Thomas, Eliassen, Aud K., Fauske, Lars, Matre, Guri, Eiken, Hans Geir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2005
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850610/
https://www.ncbi.nlm.nih.gov/pubmed/15735322
http://dx.doi.org/10.1155/2005/542928

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