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Association and Linkage Disequilibrium Analyses of APOE Polymorphisms in Atherosclerosis

Background: Apolipoprotein E (apo E) plays a major role in lipid metabolism, and its genetic variations have been associated with cardiovascular risk. The objective of this study was to investigate the influence of the APOE promoter (−491 A/T, −427 T/C and −219 G/T) and coding region (APOE ɛ2/ɛ3/ɛ4)...

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Detalles Bibliográficos
Autores principales: Artieda, Marta, Gañán, Alberto, Cenarro, Ana, García-Otín, Ángel Luis, Jericó, Ivonne, Civeira, Fernando, Pocoví, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850622/
https://www.ncbi.nlm.nih.gov/pubmed/18219091
http://dx.doi.org/10.1155/2008/650410