Cargando…

Functional effect of Saffron supplementation and risk genotypes in early age-related macular degeneration: a preliminary report

BACKGROUND: To determine whether the functional effects of oral supplementation with Saffron, a natural compound that proved to be neuroprotective in early age-related macular degeneration, are influenced by complement factor H (CFH) and age-related maculopathy susceptibility 2 (ARMS2) risk genotype...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marangoni, Dario, Falsini, Benedetto, Piccardi, Marco, Ambrosio, Lucia, Minnella, Angelo Maria, Savastano, Maria Cristina, Bisti, Silvia, Maccarone, Rita, Fadda, Antonello, Mello, Enrica, Concolino, Paola, Capoluongo, Ettore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850693/ https://www.ncbi.nlm.nih.gov/pubmed/24067115 http://dx.doi.org/10.1186/1479-5876-11-228

Ejemplares similares

A Longitudinal Follow-Up Study of Saffron Supplementation in Early Age-Related Macular Degeneration: Sustained Benefits to Central Retinal Function
por: Piccardi, M., et al.
Publicado: (2012)

Antioxidant Saffron and Central Retinal Function in ABCA4-Related Stargardt Macular Dystrophy
por: Piccardi, Marco, et al.
Publicado: (2019)

Retinal Pigment Epithelial and Outer Retinal Atrophy in Age-Related Macular Degeneration: Correlation with Macular Function
por: Savastano, Maria C., et al.
Publicado: (2020)

Macular Function in Early and Intermediate Age-related Macular Degeneration: Correlation with the Simplified Thea Risk Assessment Scale (STARS)
por: Minnella, Angelo Maria, et al.
Publicado: (2020)

Saffron: A Multitask Neuroprotective Agent for Retinal Degenerative Diseases
por: Di Marco, Stefano, et al.
Publicado: (2019)

Correlation of Macular Focal Electroretinogram with Ellipsoid Zone Extension in Stargardt Disease
por: Abed, Edoardo, et al.
Publicado: (2017)

Subretinal Pigment Epithelium Illumination Combined With Focal Electroretinogram and Visual Acuity for Early Diagnosis and Prognosis of Non-Exudative Age-Related Macular Degeneration: New Insights for Personalized Medicine
por: Savastano, Maria Cristina, et al.
Publicado: (2022)

Macular impairment in mitochondrial diseases: a potential biomarker of disease severity
por: Primiano, Guido, et al.
Publicado: (2020)

Successful long-term management of choroidal neovascularization secondary to angioid streaks in a patient with pseudoxanthoma elasticum: a case report
por: Savastano, Maria Cristina, et al.
Publicado: (2014)

A new CYP21A1P/CYP21A2 chimeric gene identified in an Italian woman suffering from classical congenital adrenal hyperplasia form
por: Concolino, Paola, et al.
Publicado: (2009)

Saffron: Chemical Composition and Neuroprotective Activity
por: Maggi, Maria Anna, et al.
Publicado: (2020)

Intravitreal Fluocinolone Acetonide for Diabetic Macular Edema: Long-Term Effect and Structure/Function Correlation
por: Minnella, Angelo Maria, et al.
Publicado: (2022)

Genetic characteristics of 234 Italian patients with macular and cone/cone-rod dystrophy
por: Falsini, Benedetto, et al.
Publicado: (2022)

Modulation of Type-1 and Type-2 Cannabinoid Receptors by Saffron in a Rat Model of Retinal Neurodegeneration
por: Maccarone, Rita, et al.
Publicado: (2016)

Choriocapillaris Vascular Density Changes: Healthy vs. Advanced Exudative Age-Related Macular Degeneration Previously Treated with Multiple Anti-VEGF Intravitreal Injections
por: Savastano, Maria Cristina, et al.
Publicado: (2021)

Artificial Intelligence and OCT Angiography in Full Thickness Macular Hole. New Developments for Personalized Medicine
por: Rizzo, Stanislao, et al.
Publicado: (2021)

Choroidal Thickness Changes After Intravitreal Aflibercept Injections in Treatment-Naïve Neovascular AMD
por: Minnella, Angelo Maria, et al.
Publicado: (2022)

Vitamin D and Age-Related Macular Degeneration
por: Garcia Layana, Alfredo, et al.
Publicado: (2017)

Efficacy of Hydroponically Cultivated Saffron in the Preservation of Retinal Pigment Epithelium
por: Di Paolo, Mattia, et al.
Publicado: (2023)

Correction: Rizzo et al. Artificial Intelligence and OCT Angiography in Full Thickness Macular Hole. New Developments for Personalized Medicine. Diagnostics 2021, 11, 2319
por: Rizzo, Stanislao, et al.
Publicado: (2022)

Swept source optical coherence tomography and optical coherence tomography angiography in pediatric enhanced S-cone syndrome: a case report
por: Minnella, Angelo Maria, et al.
Publicado: (2018)

Retinal Morpho-Functional Changes Following 0.19 mg Fluocinolone Acetonide Intravitreal Implant for Chronic Diabetic Macular Edema
por: Minnella, Angelo Maria, et al.
Publicado: (2021)

Artificial Intelligence for Evaluation of Retinal Vasculopathy in Facioscapulohumeral Dystrophy Using OCT Angiography: A Case Series
por: Maceroni, Martina, et al.
Publicado: (2023)

Preliminary molecular evidence associating a novel BRCA1 synonymous variant with hereditary ovarian cancer syndrome
por: Minucci, Angelo, et al.
Publicado: (2018)

Retinal capillary involvement in early post-COVID-19 patients: a healthy controlled study
por: Savastano, Maria Cristina, et al.
Publicado: (2021)

The Role of Diet, Micronutrients and the Gut Microbiota in Age-Related Macular Degeneration: New Perspectives from the Gut–Retina Axis
por: Rinninella, Emanuele, et al.
Publicado: (2018)

Possible Retinal Impairment Secondary to Ritonavir Use in SARS-CoV-2 Patients: A Narrative Systematic Review
por: Cozzupoli, Grazia Maria, et al.
Publicado: (2020)

Combined Intravitreal Dexamethasone Implant and Cataract Surgery in Patients with Diabetic Retinopathy: Effect on Retinal Morphology and Function
por: Minnella, Angelo Maria, et al.
Publicado: (2020)

Sequential PBM–Saffron Treatment in an Animal Model of Retinal Degeneration
por: Di Paolo, Mattia
Publicado: (2021)

A Whole Germline BRCA2 Gene Deletion: How to Learn from CNV In Silico Analysis
por: Scaglione, Giovanni Luca, et al.
Publicado: (2018)

USH2A-Related Retinitis Pigmentosa: Staging of Disease Severity and Morpho-Functional Studies
por: Falsini, Benedetto, et al.
Publicado: (2021)

Retinitis Pigmentosa Associated with EYS Gene Mutations: Disease Severity Staging and Central Retina Atrophy
por: Placidi, Giorgio, et al.
Publicado: (2023)

The Impact of Oxidative Stress on Blood-Retinal Barrier Physiology in Age-Related Macular Degeneration
por: Tisi, Annamaria, et al.
Publicado: (2021)

BRCA1 and BRCA2 Testing through Next Generation Sequencing in a Small Cohort of Italian Breast/Ovarian Cancer Patients: Novel Pathogenic and Unknown Clinical Significance Variants
por: Concolino, Paola, et al.
Publicado: (2019)

Short-term Outcomes of Saffron Supplementation in Patients with Age-related Macular Degeneration: A Double-blind, Placebo-controlled, Randomized Trial
por: LASHAY, Alireza, et al.
Publicado: (2016)

BRCA testing delay during the COVID-19 pandemic: How to act?
por: Minucci, Angelo, et al.
Publicado: (2020)

Gene and noncoding RNA regulation underlying photoreceptor protection: microarray study of dietary antioxidant saffron and photobiomodulation in rat retina
por: Natoli, Riccardo, et al.
Publicado: (2010)

Incidental Finding of a Homozygous p.M348K Asymptomatic Italian Patient Confirms the Many Faces of Cystic Fibrosis
por: Molinario, Rossana, et al.
Publicado: (2015)

Short-Term Assessment of Intravitreal Dexamethasone Implant Using Enhanced-Depth Image Optical Coherence Tomography and Optical Coherence Tomography Angiography in Patients with Retinal Vascular Diseases
por: Minnella, Angelo Maria, et al.
Publicado: (2018)

Farming for Pharming: Novel Hydroponic Process in Contained Environment for Efficient Pharma-Grade Production of Saffron
por: Nardi, Luca, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_fidsdlllibnidui1cvtec4t2ba