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The BCL2-938 C > A promoter polymorphism is associated with risk group classification in children with acute lymphoblastic leukemia

BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. While current treatment regimens achieve almost 80% overall survival, long-term side effects of chemotherapeutic agents can be severe. The functional BCL2-938C > A promoter polymorphism is known to influence the b...

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Detalles Bibliográficos
Autores principales: Künkele, Annette, Grosse-Lordemann, Anja, Schramm, Alexander, Eggert, Angelika, Schulte, Johannes H, Bachmann, Hagen S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850706/
https://www.ncbi.nlm.nih.gov/pubmed/24088574
http://dx.doi.org/10.1186/1471-2407-13-452