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Quantitative trait loci analysis reveals candidate genes implicated in regulating functional deficit and CNS vascular permeability in CD8 T cell-initiated blood–brain barrier disruption

BACKGROUND: Blood–brain barrier (BBB) disruption is an integral feature of numerous neurological disorders. However, there is a relative lack of knowledge regarding the underlying molecular mechanisms of immune-mediated BBB disruption. We have previously shown that CD8 T cells and perforin play crit...

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Detalles Bibliográficos
Autores principales:	Johnson, Holly L, Hanson, Lisa M, Chen, Yi, Bieber, Allan J, Buono, Russell J, Ferraro, Thomas N, Pirko, Istvan, Johnson, Aaron J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850781/ https://www.ncbi.nlm.nih.gov/pubmed/24090483 http://dx.doi.org/10.1186/1471-2164-14-678

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