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Creating Hybrid Genes by Homologous Recombination
Recombination of homologous genes is a powerful mechanism for generating sequence diversity, and can be applied to protein analysis and directed evolution. In vitro recombination methods such as DNA shuffling are very flexible and can give hybrid genes with multiple crossovers; they have been used e...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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IOS Press
2000
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850801/ https://www.ncbi.nlm.nih.gov/pubmed/11360826 http://dx.doi.org/10.1155/2000/596468 |