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A Mononucleotide Markers Panel to Identify hMLH1/hMSH2 Germline Mutations
Hereditary NonPolyposis Colorectal Cancer (Lynch syndrome) is an autosomal dominant disease caused by germline mutations in a class of genes deputed to maintain genomic integrity during cell replication, mutations result in a generalized genomic instability, particularly evident at microsatellite lo...
Autores principales: | Pedroni, M., Roncari, B., Maffei, S., Losi, L., Scarselli, A., Di Gregorio, C., Marino, M., Roncucci, L., Benatti, P., Ponti, G., Rossi, G., Menigatti, M., Viel, A., Genuardi, M., de Leon, M. Ponz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850839/ https://www.ncbi.nlm.nih.gov/pubmed/17473388 http://dx.doi.org/10.1155/2007/703129 |
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