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Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis
BACKGROUND: Components of the innate immune complement system have been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS); however, a comprehensive examination of complement expression in this disease has not been performed. This study therefore aimed to determine the expression...
Autores principales: | Lee, John D, Kamaruzaman, Nur A, Fung, Jenny NT, Taylor, Stephen M, Turner, Bradley J, Atkin, Julie D, Woodruff, Trent M, Noakes, Peter G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850877/ https://www.ncbi.nlm.nih.gov/pubmed/24067070 http://dx.doi.org/10.1186/1742-2094-10-119 |
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