Genomic pathway analysis reveals that EZH2 and HDAC4 represent mutually exclusive epigenetic pathways across human cancers

BACKGROUND: Alterations in epigenetic marks, including methylation or acetylation, are common in human cancers. For many epigenetic pathways, however, direct measures of activity are unknown, making their role in various cancers difficult to assess. Gene expression signatures facilitate the examinat...

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Detalles Bibliográficos
Autores principales: Cohen, Adam L, Piccolo, Stephen R, Cheng, Luis, Soldi, Rafaella, Han, Bing, Johnson, W Evan, Bild, Andrea H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850967/
https://www.ncbi.nlm.nih.gov/pubmed/24079712
http://dx.doi.org/10.1186/1755-8794-6-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850967/
https://www.ncbi.nlm.nih.gov/pubmed/24079712
http://dx.doi.org/10.1186/1755-8794-6-35

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