Cargando…
Drug activity prediction using multiple-instance learning via joint instance and feature selection
BACKGROUND: In drug discovery and development, it is crucial to determine which conformers (instances) of a given molecule are responsible for its observed biological activity and at the same time to recognize the most representative subset of features (molecular descriptors). Due to experimental di...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850986/ https://www.ncbi.nlm.nih.gov/pubmed/24267824 http://dx.doi.org/10.1186/1471-2105-14-S14-S16 |