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Cytological diagnosis of adult-type fibrosarcoma of the neck in an elderly patient. Report of one case and review of the literature

BACKGROUND: Fibrosarcoma (FS) accounts for about 3% of all soft tissue sarcomas. It may arise in any area of the body, but it is relative rare in the head and neck district. Fine-needle cytology (FNC) is widely used in the diagnosis of neoplastic and non-neoplastic lesions of soft tissue. This artic...

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Autores principales: Cozzolino, Immacolata, Caleo, Alessia, Di Crescenzo, Vincenzo, Cinelli, Mariapia, Carlomagno, Chiara, Garzi, Alfredo, Vitale, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850999/
https://www.ncbi.nlm.nih.gov/pubmed/24266985
http://dx.doi.org/10.1186/1471-2482-13-S2-S42
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author Cozzolino, Immacolata
Caleo, Alessia
Di Crescenzo, Vincenzo
Cinelli, Mariapia
Carlomagno, Chiara
Garzi, Alfredo
Vitale, Mario
author_facet Cozzolino, Immacolata
Caleo, Alessia
Di Crescenzo, Vincenzo
Cinelli, Mariapia
Carlomagno, Chiara
Garzi, Alfredo
Vitale, Mario
author_sort Cozzolino, Immacolata
collection PubMed
description BACKGROUND: Fibrosarcoma (FS) accounts for about 3% of all soft tissue sarcomas. It may arise in any area of the body, but it is relative rare in the head and neck district. Fine-needle cytology (FNC) is widely used in the diagnosis of neoplastic and non-neoplastic lesions of soft tissue. This article describes a case of FS of the neck diagnosed by FNC. METHODS: FNC was performed in a sub-fascial supraclavicular mass of an elderly patient under ultrasound (US) control. FNC was used to prepare cytological smears that were conventionally and immunocytochemically (ICC) stained. RESULTS: Smears showed a monomorphous spindle cell population and were positive at ICC for Vimentin and negative for CKAE1AE3, Actin, S-100, CD68, CT and PAX-8. The cytological diagnosis was confirmed by histological diagnosis. The patient underwent surgical resection and subsequent radiotherapy. CONCLUSIONS: FNC diagnosis of FS is reliable and accurate and may be conveniently used in the scheduling of surgical procedures, when needed, avoiding the treatment of benign nodules.
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spelling pubmed-38509992013-12-13 Cytological diagnosis of adult-type fibrosarcoma of the neck in an elderly patient. Report of one case and review of the literature Cozzolino, Immacolata Caleo, Alessia Di Crescenzo, Vincenzo Cinelli, Mariapia Carlomagno, Chiara Garzi, Alfredo Vitale, Mario BMC Surg Research Article BACKGROUND: Fibrosarcoma (FS) accounts for about 3% of all soft tissue sarcomas. It may arise in any area of the body, but it is relative rare in the head and neck district. Fine-needle cytology (FNC) is widely used in the diagnosis of neoplastic and non-neoplastic lesions of soft tissue. This article describes a case of FS of the neck diagnosed by FNC. METHODS: FNC was performed in a sub-fascial supraclavicular mass of an elderly patient under ultrasound (US) control. FNC was used to prepare cytological smears that were conventionally and immunocytochemically (ICC) stained. RESULTS: Smears showed a monomorphous spindle cell population and were positive at ICC for Vimentin and negative for CKAE1AE3, Actin, S-100, CD68, CT and PAX-8. The cytological diagnosis was confirmed by histological diagnosis. The patient underwent surgical resection and subsequent radiotherapy. CONCLUSIONS: FNC diagnosis of FS is reliable and accurate and may be conveniently used in the scheduling of surgical procedures, when needed, avoiding the treatment of benign nodules. BioMed Central 2013-10-08 /pmc/articles/PMC3850999/ /pubmed/24266985 http://dx.doi.org/10.1186/1471-2482-13-S2-S42 Text en Copyright © 2013 Cozzolino et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Cozzolino, Immacolata
Caleo, Alessia
Di Crescenzo, Vincenzo
Cinelli, Mariapia
Carlomagno, Chiara
Garzi, Alfredo
Vitale, Mario
Cytological diagnosis of adult-type fibrosarcoma of the neck in an elderly patient. Report of one case and review of the literature
title Cytological diagnosis of adult-type fibrosarcoma of the neck in an elderly patient. Report of one case and review of the literature
title_full Cytological diagnosis of adult-type fibrosarcoma of the neck in an elderly patient. Report of one case and review of the literature
title_fullStr Cytological diagnosis of adult-type fibrosarcoma of the neck in an elderly patient. Report of one case and review of the literature
title_full_unstemmed Cytological diagnosis of adult-type fibrosarcoma of the neck in an elderly patient. Report of one case and review of the literature
title_short Cytological diagnosis of adult-type fibrosarcoma of the neck in an elderly patient. Report of one case and review of the literature
title_sort cytological diagnosis of adult-type fibrosarcoma of the neck in an elderly patient. report of one case and review of the literature
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850999/
https://www.ncbi.nlm.nih.gov/pubmed/24266985
http://dx.doi.org/10.1186/1471-2482-13-S2-S42
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