Cargando…
Zinc inhibits osteoclast differentiation by suppression of Ca(2+)-Calcineurin-NFATc1 signaling pathway
BACKGROUND: Zinc, an essential trace element, inhibits osteoclast differentiation in vitro and in vivo. The molecular mechanism for the inhibitory effect of zinc, however, is poorly understood. The purpose of this study was to investigate the effect of zinc and determine its molecular mechanism on r...
Autores principales: | Park, Kwang Hwan, Park, Boryung, Yoon, Dong Suk, Kwon, Seung-Hyun, Shin, Dong Min, Lee, Jin Woo, Lee, Hyun Gyu, Shim, Jae-Hyuck, Park, Jeon Han, Lee, Jae Myun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851046/ https://www.ncbi.nlm.nih.gov/pubmed/24088289 http://dx.doi.org/10.1186/1478-811X-11-74 |
Ejemplares similares
-
mTORC1 impedes osteoclast differentiation via calcineurin and NFATc1
por: Huynh, HoangDinh, et al.
Publicado: (2018) -
Betulin Suppresses Osteoclast Formation via Down-Regulating NFATc1
por: Kim, Kwang-Jin, et al.
Publicado: (2018) -
Chaenomelis fructus inhibits osteoclast differentiation by suppressing NFATc1 expression and prevents ovariectomy-induced osteoporosis
por: Kim, Minsun, et al.
Publicado: (2020) -
CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts
por: Greenblatt, Matthew B., et al.
Publicado: (2015) -
Arctigenin Inhibits Osteoclast Differentiation and Function by Suppressing Both Calcineurin-Dependent and Osteoblastic Cell-Dependent NFATc1 Pathways
por: Yamashita, Teruhito, et al.
Publicado: (2014)