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Claudin Proteins in Ovarian Cancer
Members of the claudin family of tight junction proteins have been found altered in several malignancies, including ovarian cancer. Because claudin-3 and -4 are elevated in the vast majority of ovarian tumors, they may represent useful biomarkers for detection and prognosis, as well as ideal targets...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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IOS Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851116/ https://www.ncbi.nlm.nih.gov/pubmed/18057528 http://dx.doi.org/10.1155/2007/674058 |
| Sumario: | Members of the claudin family of tight junction proteins have been found altered in several malignancies, including ovarian cancer. Because claudin-3 and -4 are elevated in the vast majority of ovarian tumors, they may represent useful biomarkers for detection and prognosis, as well as ideal targets for therapy using the Clostridium perfringens enterotoxin. |
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