Cargando…
Low Birth Weight, Small for Gestational Age and Preterm Births before and after the Economic Collapse in Iceland: A Population Based Cohort Study
OBJECTIVE: Infants born small for gestational age (SGA) or preterm have increased rates of perinatal morbidity and mortality. Stressful events have been suggested as potential contributors to preterm birth (PB) and low birth weight (LBW). We studied the effect of the 2008 economic collapse in Icelan...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851132/ https://www.ncbi.nlm.nih.gov/pubmed/24324602 http://dx.doi.org/10.1371/journal.pone.0080499 |
_version_ | 1782294231600070656 |
---|---|
author | Eiríksdóttir, Védís Helga Ásgeirsdóttir, Tinna Laufey Bjarnadóttir, Ragnheiður Ingibjörg Kaestner, Robert Cnattingius, Sven Valdimarsdóttir, Unnur Anna |
author_facet | Eiríksdóttir, Védís Helga Ásgeirsdóttir, Tinna Laufey Bjarnadóttir, Ragnheiður Ingibjörg Kaestner, Robert Cnattingius, Sven Valdimarsdóttir, Unnur Anna |
author_sort | Eiríksdóttir, Védís Helga |
collection | PubMed |
description | OBJECTIVE: Infants born small for gestational age (SGA) or preterm have increased rates of perinatal morbidity and mortality. Stressful events have been suggested as potential contributors to preterm birth (PB) and low birth weight (LBW). We studied the effect of the 2008 economic collapse in Iceland on the risks of adverse birth outcomes. STUDY DESIGN: The study population constituted all Icelandic women giving birth to live-born singletons from January 1(st) 2006 to December 31(st) 2009. LBW infants were defined as those weighing <2500 grams at birth, PB infants as those born before 37 weeks of gestation and SGA as those with a birth weight for gestational age more than 2 standard deviations (SD's) below the mean according to the Swedish fetal growth curve. We used logistic regression analysis to estimate odds ratios [OR] and corresponding 95 percent confidence intervals [95% CI] of adverse birth outcomes by exposure to calendar time of the economic collapse, i.e. after October 6(th) 2008. RESULTS: Compared to the preceding period, we observed an increased adjusted odds in LBW-deliveries following the collapse (aOR = 1.24, 95% CI [1.02, 1.52]), particularly among infants born to mothers younger than 25 years (aOR = 1.85, 95% CI [1.25, 2.72]) and not working mothers (aOR = 1.61, 95% CI [1.10, 2.35]). Similarly, we found a tendency towards higher incidence of SGA-births (aOR = 1.14, 95% CI [0.86, 1.51]) particularly among children born to mothers younger than 25 years (aOR = 1.87, 95% CI [1.09, 3.23]) and not working mothers (aOR = 1.86, 95% CI [1.09, 3.17]). No change in risk of PB was observed. The increase of LBW was most distinct 6–9 months after the collapse. CONCLUSION: The results suggest an increase in risk of LBW shortly after the collapse of the Icelandic national economy. The increase in LBW seems to be driven by reduced fetal growth rate rather than shorter gestation. |
format | Online Article Text |
id | pubmed-3851132 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-38511322013-12-09 Low Birth Weight, Small for Gestational Age and Preterm Births before and after the Economic Collapse in Iceland: A Population Based Cohort Study Eiríksdóttir, Védís Helga Ásgeirsdóttir, Tinna Laufey Bjarnadóttir, Ragnheiður Ingibjörg Kaestner, Robert Cnattingius, Sven Valdimarsdóttir, Unnur Anna PLoS One Research Article OBJECTIVE: Infants born small for gestational age (SGA) or preterm have increased rates of perinatal morbidity and mortality. Stressful events have been suggested as potential contributors to preterm birth (PB) and low birth weight (LBW). We studied the effect of the 2008 economic collapse in Iceland on the risks of adverse birth outcomes. STUDY DESIGN: The study population constituted all Icelandic women giving birth to live-born singletons from January 1(st) 2006 to December 31(st) 2009. LBW infants were defined as those weighing <2500 grams at birth, PB infants as those born before 37 weeks of gestation and SGA as those with a birth weight for gestational age more than 2 standard deviations (SD's) below the mean according to the Swedish fetal growth curve. We used logistic regression analysis to estimate odds ratios [OR] and corresponding 95 percent confidence intervals [95% CI] of adverse birth outcomes by exposure to calendar time of the economic collapse, i.e. after October 6(th) 2008. RESULTS: Compared to the preceding period, we observed an increased adjusted odds in LBW-deliveries following the collapse (aOR = 1.24, 95% CI [1.02, 1.52]), particularly among infants born to mothers younger than 25 years (aOR = 1.85, 95% CI [1.25, 2.72]) and not working mothers (aOR = 1.61, 95% CI [1.10, 2.35]). Similarly, we found a tendency towards higher incidence of SGA-births (aOR = 1.14, 95% CI [0.86, 1.51]) particularly among children born to mothers younger than 25 years (aOR = 1.87, 95% CI [1.09, 3.23]) and not working mothers (aOR = 1.86, 95% CI [1.09, 3.17]). No change in risk of PB was observed. The increase of LBW was most distinct 6–9 months after the collapse. CONCLUSION: The results suggest an increase in risk of LBW shortly after the collapse of the Icelandic national economy. The increase in LBW seems to be driven by reduced fetal growth rate rather than shorter gestation. Public Library of Science 2013-12-04 /pmc/articles/PMC3851132/ /pubmed/24324602 http://dx.doi.org/10.1371/journal.pone.0080499 Text en © 2013 Eiríksdóttir et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Eiríksdóttir, Védís Helga Ásgeirsdóttir, Tinna Laufey Bjarnadóttir, Ragnheiður Ingibjörg Kaestner, Robert Cnattingius, Sven Valdimarsdóttir, Unnur Anna Low Birth Weight, Small for Gestational Age and Preterm Births before and after the Economic Collapse in Iceland: A Population Based Cohort Study |
title | Low Birth Weight, Small for Gestational Age and Preterm Births before and after the Economic Collapse in Iceland: A Population Based Cohort Study |
title_full | Low Birth Weight, Small for Gestational Age and Preterm Births before and after the Economic Collapse in Iceland: A Population Based Cohort Study |
title_fullStr | Low Birth Weight, Small for Gestational Age and Preterm Births before and after the Economic Collapse in Iceland: A Population Based Cohort Study |
title_full_unstemmed | Low Birth Weight, Small for Gestational Age and Preterm Births before and after the Economic Collapse in Iceland: A Population Based Cohort Study |
title_short | Low Birth Weight, Small for Gestational Age and Preterm Births before and after the Economic Collapse in Iceland: A Population Based Cohort Study |
title_sort | low birth weight, small for gestational age and preterm births before and after the economic collapse in iceland: a population based cohort study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851132/ https://www.ncbi.nlm.nih.gov/pubmed/24324602 http://dx.doi.org/10.1371/journal.pone.0080499 |
work_keys_str_mv | AT eiriksdottirvedishelga lowbirthweightsmallforgestationalageandpretermbirthsbeforeandaftertheeconomiccollapseinicelandapopulationbasedcohortstudy AT asgeirsdottirtinnalaufey lowbirthweightsmallforgestationalageandpretermbirthsbeforeandaftertheeconomiccollapseinicelandapopulationbasedcohortstudy AT bjarnadottirragnheiðuringibjorg lowbirthweightsmallforgestationalageandpretermbirthsbeforeandaftertheeconomiccollapseinicelandapopulationbasedcohortstudy AT kaestnerrobert lowbirthweightsmallforgestationalageandpretermbirthsbeforeandaftertheeconomiccollapseinicelandapopulationbasedcohortstudy AT cnattingiussven lowbirthweightsmallforgestationalageandpretermbirthsbeforeandaftertheeconomiccollapseinicelandapopulationbasedcohortstudy AT valdimarsdottirunnuranna lowbirthweightsmallforgestationalageandpretermbirthsbeforeandaftertheeconomiccollapseinicelandapopulationbasedcohortstudy |