MYC, FBXW7 and TP53 copy number variation and expression in Gastric Cancer

BACKGROUND: MYC deregulation is a common event in gastric carcinogenesis, usually as a consequence of gene amplification, chromosomal translocations, or posttranslational mechanisms. FBXW7 is a p53-controlled tumor-suppressor that plays a role in the regulation of cell cycle exit and reentry via MYC...

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Detalles Bibliográficos
Autores principales: Calcagno, Danielle Queiroz, Freitas, Vanessa Morais, Leal, Mariana Ferreira, de Souza, Carolina Rosal Teixeira, Demachki, Samia, Montenegro, Raquel, Assumpção, Paulo Pimentel, Khayat, André Salim, Smith, Marília de Arruda Cardoso, dos Santos, Andrea Kely Campos Ribeiro, Burbano, Rommel Rodriguez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851138/
https://www.ncbi.nlm.nih.gov/pubmed/24053468
http://dx.doi.org/10.1186/1471-230X-13-141

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