Axillary lymphadenectomy for breast cancer in elderly patients and fibrin glue

BACKGROUND: Axillary lymphadenectomy or sentinel biopsy is integral part of breast cancer treatment, yet seroma formation occurs in 15-85% of cases. Among methods employed to reduce seroma magnitude and duration, fibrin glue has been proposed in numerous studies with controversial results. METHODS:...

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Detalles Bibliográficos
Autores principales: Docimo, Giovanni, Limongelli, Paolo, Conzo, Giovanni, Gili, Simona, Bosco, Alfonso, Rizzuto, Antonia, Amoroso, Vincenzo, Marsico, Salvatore, Leone, Nicola, Esposito, Antonio, Vitiello, Chiara, Fei, Landino, Parmeggiani, Domenico, Docimo, Ludovico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851152/
https://www.ncbi.nlm.nih.gov/pubmed/24266959
http://dx.doi.org/10.1186/1471-2482-13-S2-S8
Descripción
Sumario:BACKGROUND: Axillary lymphadenectomy or sentinel biopsy is integral part of breast cancer treatment, yet seroma formation occurs in 15-85% of cases. Among methods employed to reduce seroma magnitude and duration, fibrin glue has been proposed in numerous studies with controversial results. METHODS: Thirty patients over 60 years underwent quadrantectomy or mastectomy with level I/II axillary lymphadenectomy; a suction drain was fitted in all patients. Fibrin glue spray were applied to the axillary fossa in 15 patients; the other 15 patients were treated with harmonic scalpel. RESULTS: Suction drainage was removed between post-operative Days 3 and 4. Seroma magnitude and duration were not significant in patients receiving fibrin glue compared with the harmonic scalpel group. CONCLUSIONS: Use of fibrin glue does not always prevent seroma formation, but can reduce seroma magnitude, duration and necessary evacuative punctures.

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