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Local anesthesia for treatment of hernia in elder patients: Levobupicavaine or Bupivacaine?

BACKGROUND: Inguinal hernia is one of the most common diseases in the elderly. Treatment of this pathology is exclusively surgical and relies almost always on the use of local anesthesia. While in the past hernia surgery was carried out mainly by general anesthesia, in recent years there has been gr...

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Autores principales: Compagna, Rita, Vigliotti, Gabriele, Bianco, Tommaso, Amato, Maurizio, Rossi, Roberto, Fappiano, Francesca, Accurso, Antonello, Danzi, Michele, Aprea, Giovanni, Amato, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851157/
https://www.ncbi.nlm.nih.gov/pubmed/24267484
http://dx.doi.org/10.1186/1471-2482-13-S2-S30
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author Compagna, Rita
Vigliotti, Gabriele
Bianco, Tommaso
Amato, Maurizio
Rossi, Roberto
Fappiano, Francesca
Accurso, Antonello
Danzi, Michele
Aprea, Giovanni
Amato, Bruno
author_facet Compagna, Rita
Vigliotti, Gabriele
Bianco, Tommaso
Amato, Maurizio
Rossi, Roberto
Fappiano, Francesca
Accurso, Antonello
Danzi, Michele
Aprea, Giovanni
Amato, Bruno
author_sort Compagna, Rita
collection PubMed
description BACKGROUND: Inguinal hernia is one of the most common diseases in the elderly. Treatment of this pathology is exclusively surgical and relies almost always on the use of local anesthesia. While in the past hernia surgery was carried out mainly by general anesthesia, in recent years there has been growing emphasis on the role of local anesthesia. METHODS: The aim of our study was to compare intra-and postoperative analgesia obtained by the use of levobupivacaine to the same obtained by bupivacaine. Bupivacaine is one of the main local anesthetics used in the intervention of inguinal hernioplasty. Levobupivacaine is an enantiomer of racemic bupivacaine with less cardiotoxicity and neurotoxicity. The study was conducted from March 2011 to March 2013. We collected data of eighty patients, male and female, aged between 65 and 86 years, who underwent inguinal hernioplasty with local anesthesia. RESULTS: Evaluation of intra-operatively pain shows that minimal pain is the same in both groups. Mild pain was more frequent in the group who used levobupivacaine. Moderate pain was slightly more frequent in the group who used bupivacaine. Only one reported intense pain. Two drugs seem to have the same effect at a distance of six, twelve, eighteen and twentyfour hours. Bupivacaine shows a significantly higher number of complications, as already demonstrated by previous studies. Degree of satisfaction expressed by patients has been the same in the two groups. Levobupivacaine group has shown a greater request for paracetamol while patients who experienced bupivacaine have showed a higher request of other analgesics. CONCLUSIONS: Clinical efficacy of levobupivacaine and racemic bupivacaine are actually similar, when used under local intervention of inguinal hernioplasty. In the field of ambulatorial surgery our working group prefers levobupivacaine for its fewer side effects and for its easy handling.
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spelling pubmed-38511572013-12-13 Local anesthesia for treatment of hernia in elder patients: Levobupicavaine or Bupivacaine? Compagna, Rita Vigliotti, Gabriele Bianco, Tommaso Amato, Maurizio Rossi, Roberto Fappiano, Francesca Accurso, Antonello Danzi, Michele Aprea, Giovanni Amato, Bruno BMC Surg Research Article BACKGROUND: Inguinal hernia is one of the most common diseases in the elderly. Treatment of this pathology is exclusively surgical and relies almost always on the use of local anesthesia. While in the past hernia surgery was carried out mainly by general anesthesia, in recent years there has been growing emphasis on the role of local anesthesia. METHODS: The aim of our study was to compare intra-and postoperative analgesia obtained by the use of levobupivacaine to the same obtained by bupivacaine. Bupivacaine is one of the main local anesthetics used in the intervention of inguinal hernioplasty. Levobupivacaine is an enantiomer of racemic bupivacaine with less cardiotoxicity and neurotoxicity. The study was conducted from March 2011 to March 2013. We collected data of eighty patients, male and female, aged between 65 and 86 years, who underwent inguinal hernioplasty with local anesthesia. RESULTS: Evaluation of intra-operatively pain shows that minimal pain is the same in both groups. Mild pain was more frequent in the group who used levobupivacaine. Moderate pain was slightly more frequent in the group who used bupivacaine. Only one reported intense pain. Two drugs seem to have the same effect at a distance of six, twelve, eighteen and twentyfour hours. Bupivacaine shows a significantly higher number of complications, as already demonstrated by previous studies. Degree of satisfaction expressed by patients has been the same in the two groups. Levobupivacaine group has shown a greater request for paracetamol while patients who experienced bupivacaine have showed a higher request of other analgesics. CONCLUSIONS: Clinical efficacy of levobupivacaine and racemic bupivacaine are actually similar, when used under local intervention of inguinal hernioplasty. In the field of ambulatorial surgery our working group prefers levobupivacaine for its fewer side effects and for its easy handling. BioMed Central 2013-10-08 /pmc/articles/PMC3851157/ /pubmed/24267484 http://dx.doi.org/10.1186/1471-2482-13-S2-S30 Text en Copyright © 2013 Compagna et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Compagna, Rita
Vigliotti, Gabriele
Bianco, Tommaso
Amato, Maurizio
Rossi, Roberto
Fappiano, Francesca
Accurso, Antonello
Danzi, Michele
Aprea, Giovanni
Amato, Bruno
Local anesthesia for treatment of hernia in elder patients: Levobupicavaine or Bupivacaine?
title Local anesthesia for treatment of hernia in elder patients: Levobupicavaine or Bupivacaine?
title_full Local anesthesia for treatment of hernia in elder patients: Levobupicavaine or Bupivacaine?
title_fullStr Local anesthesia for treatment of hernia in elder patients: Levobupicavaine or Bupivacaine?
title_full_unstemmed Local anesthesia for treatment of hernia in elder patients: Levobupicavaine or Bupivacaine?
title_short Local anesthesia for treatment of hernia in elder patients: Levobupicavaine or Bupivacaine?
title_sort local anesthesia for treatment of hernia in elder patients: levobupicavaine or bupivacaine?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851157/
https://www.ncbi.nlm.nih.gov/pubmed/24267484
http://dx.doi.org/10.1186/1471-2482-13-S2-S30
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