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The ALS/FTLD-related RNA-binding proteins TDP-43 and FUS have common downstream RNA targets in cortical neurons()

TDP-43 and FUS are linked to amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), and loss of function of either protein contributes to these neurodegenerative conditions. To elucidate the TDP-43- and FUS-regulated pathophysiological RNA metabolism cascades, we assessed...

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Detalles Bibliográficos
Autores principales:	Honda, Daiyu, Ishigaki, Shinsuke, Iguchi, Yohei, Fujioka, Yusuke, Udagawa, Tsuyoshi, Masuda, Akio, Ohno, Kinji, Katsuno, Masahisa, Sobue, Gen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851184/ https://www.ncbi.nlm.nih.gov/pubmed/24319651 http://dx.doi.org/10.1016/j.fob.2013.11.001

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