SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs)

New technologies enabling genome-wide interrogation have led to a large and rapidly growing number of autism spectrum disorder (ASD) candidate genes. Although encouraging, the volume and complexity of these data make it challenging for scientists, particularly non-geneticists, to comprehensively eva...

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Autores principales: Abrahams, Brett S, Arking, Dan E, Campbell, Daniel B, Mefford, Heather C, Morrow, Eric M, Weiss, Lauren A, Menashe, Idan, Wadkins, Tim, Banerjee-Basu, Sharmila, Packer, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851189/
https://www.ncbi.nlm.nih.gov/pubmed/24090431
http://dx.doi.org/10.1186/2040-2392-4-36
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author Abrahams, Brett S
Arking, Dan E
Campbell, Daniel B
Mefford, Heather C
Morrow, Eric M
Weiss, Lauren A
Menashe, Idan
Wadkins, Tim
Banerjee-Basu, Sharmila
Packer, Alan
author_facet Abrahams, Brett S
Arking, Dan E
Campbell, Daniel B
Mefford, Heather C
Morrow, Eric M
Weiss, Lauren A
Menashe, Idan
Wadkins, Tim
Banerjee-Basu, Sharmila
Packer, Alan
author_sort Abrahams, Brett S
collection PubMed
description New technologies enabling genome-wide interrogation have led to a large and rapidly growing number of autism spectrum disorder (ASD) candidate genes. Although encouraging, the volume and complexity of these data make it challenging for scientists, particularly non-geneticists, to comprehensively evaluate available evidence for individual genes. Described here is the Gene Scoring module within SFARI Gene 2.0 (https://gene.sfari.org/autdb/GS_Home.do), a platform developed to enable systematic community driven assessment of genetic evidence for individual genes with regard to ASD.
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spelling pubmed-38511892013-12-06 SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs) Abrahams, Brett S Arking, Dan E Campbell, Daniel B Mefford, Heather C Morrow, Eric M Weiss, Lauren A Menashe, Idan Wadkins, Tim Banerjee-Basu, Sharmila Packer, Alan Mol Autism Letter to the Editor New technologies enabling genome-wide interrogation have led to a large and rapidly growing number of autism spectrum disorder (ASD) candidate genes. Although encouraging, the volume and complexity of these data make it challenging for scientists, particularly non-geneticists, to comprehensively evaluate available evidence for individual genes. Described here is the Gene Scoring module within SFARI Gene 2.0 (https://gene.sfari.org/autdb/GS_Home.do), a platform developed to enable systematic community driven assessment of genetic evidence for individual genes with regard to ASD. BioMed Central 2013-10-03 /pmc/articles/PMC3851189/ /pubmed/24090431 http://dx.doi.org/10.1186/2040-2392-4-36 Text en Copyright © 2013 Abrahams et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letter to the Editor
Abrahams, Brett S
Arking, Dan E
Campbell, Daniel B
Mefford, Heather C
Morrow, Eric M
Weiss, Lauren A
Menashe, Idan
Wadkins, Tim
Banerjee-Basu, Sharmila
Packer, Alan
SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs)
title SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs)
title_full SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs)
title_fullStr SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs)
title_full_unstemmed SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs)
title_short SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs)
title_sort sfari gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (asds)
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851189/
https://www.ncbi.nlm.nih.gov/pubmed/24090431
http://dx.doi.org/10.1186/2040-2392-4-36
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