Developability studies before initiation of process development: Improving manufacturability of monoclonal antibodies

Monoclonal antibodies constitute a robust class of therapeutic proteins. Their stability, resistance to stress conditions and high solubility have allowed the successful development and commercialization of over 40 antibody-based drugs. Although mAbs enjoy a relatively high probability of success co...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoyu, Xu, Wei, Dukleska, Svetlana, Benchaar, Sabrina, Mengisen, Selina, Antochshuk, Valentyn, Cheung, Jason, Mann, Leslie, Babadjanova, Zulfia, Rowand, Jason, Gunawan, Rico, McCampbell, Alexander, Beaumont, Maribel, Meininger, David, Richardson, Daisy, Ambrogelly, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851230/
https://www.ncbi.nlm.nih.gov/pubmed/23883920
http://dx.doi.org/10.4161/mabs.25269

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