Purification of monoclonal antibodies by hydrophobic interaction chromatography under no-salt conditions

Hydrophobic interaction chromatography (HIC) is commonly used as a polishing step in monoclonal antibody purification processes. HIC offers an orthogonal selectivity to ion exchange chromatography and can be an effective step for aggregate clearance and host cell protein reduction. HIC, however, suf...

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Detalles Bibliográficos
Autores principales: Ghose, Sanchayita, Tao, Yinying, Conley, Lynn, Cecchini, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851231/
https://www.ncbi.nlm.nih.gov/pubmed/23884181
http://dx.doi.org/10.4161/mabs.25552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851231/
https://www.ncbi.nlm.nih.gov/pubmed/23884181
http://dx.doi.org/10.4161/mabs.25552

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