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PHDcleav: a SVM based method for predicting human Dicer cleavage sites using sequence and secondary structure of miRNA precursors

BACKGROUND: Dicer, an RNase III enzyme, plays a vital role in the processing of pre-miRNAs for generating the miRNAs. The structural and sequence features on pre-miRNA which can facilitate position and efficiency of cleavage are not well known. A precise cleavage by Dicer is crucial because an inacc...

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Detalles Bibliográficos
Autores principales:	Ahmed, Firoz, Kaundal, Rakesh, Raghava, Gajendra PS
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851333/ https://www.ncbi.nlm.nih.gov/pubmed/24267009 http://dx.doi.org/10.1186/1471-2105-14-S14-S9

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