BRCA1 1675delA and 1135insA Account for One Third of Norwegian Familial Breast-Ovarian Cancer and Are Associated with Later Disease Onset than Less Frequent Mutations

A total of 845 women from breast-ovarian cancer kindreds were enrolled in a clinical follow-up program for early disease diagnosis; 35 women were prospectively identified with cancer. In order to estimate the role of genetic factors for cancer predisposition in this well-defined set of patients, con...

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Detalles Bibliográficos
Autores principales: Borg, Åke, Dørum, Anne, Heimdal, Ketil, Mæhle, Lovise, Hovig, Eivind, Møller, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 1999
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851406/
https://www.ncbi.nlm.nih.gov/pubmed/10595257
http://dx.doi.org/10.1155/1999/278269

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