Clinical Application of Rapid Assay of Interleukin-6 in Influenza-Associated Encephalopathy

The characteristics of influenza-associated encephalopathy is the high mortality and nimble progress with coma which appears in general cases within 48 hours. Most of patients show no abnormalities in the standard blood checks on admission or in early stage. In this study we investigated if a rapid...

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Autores principales: Nakamura, Mikage, Yamanaka, Gaku, Kawashima, Hisashi, Watanabe, Yoshiaki, Ioi, Hiroaki, Kashiwagi, Yasuyo, Takekuma, Kouji, Hoshika, Akinori, Hayakawa, Mizuho, Suzuki, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2005
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851426/
https://www.ncbi.nlm.nih.gov/pubmed/16403955
http://dx.doi.org/10.1155/2005/671609
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author Nakamura, Mikage
Yamanaka, Gaku
Kawashima, Hisashi
Watanabe, Yoshiaki
Ioi, Hiroaki
Kashiwagi, Yasuyo
Takekuma, Kouji
Hoshika, Akinori
Hayakawa, Mizuho
Suzuki, Shigeru
author_facet Nakamura, Mikage
Yamanaka, Gaku
Kawashima, Hisashi
Watanabe, Yoshiaki
Ioi, Hiroaki
Kashiwagi, Yasuyo
Takekuma, Kouji
Hoshika, Akinori
Hayakawa, Mizuho
Suzuki, Shigeru
author_sort Nakamura, Mikage
collection PubMed
description The characteristics of influenza-associated encephalopathy is the high mortality and nimble progress with coma which appears in general cases within 48 hours. Most of patients show no abnormalities in the standard blood checks on admission or in early stage. In this study we investigated if a rapid assay of interleukin (IL)-6 is useful in influenza-associated encephalopathy in early stages. The levels of IL-6 in patients with influenza-associated encephalopathy did not show any significant difference compared with those in patients with febrile convulsion and rotavirus-associated convulsion. However the levels of IL-6 in severe cases were significantly higher than those of mild cases with influenza-associated encephalopathy. Consequently the rapid assay of serum IL-6 is useful to evaluate and decide the therapies.
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spelling pubmed-38514262013-12-22 Clinical Application of Rapid Assay of Interleukin-6 in Influenza-Associated Encephalopathy Nakamura, Mikage Yamanaka, Gaku Kawashima, Hisashi Watanabe, Yoshiaki Ioi, Hiroaki Kashiwagi, Yasuyo Takekuma, Kouji Hoshika, Akinori Hayakawa, Mizuho Suzuki, Shigeru Dis Markers Other The characteristics of influenza-associated encephalopathy is the high mortality and nimble progress with coma which appears in general cases within 48 hours. Most of patients show no abnormalities in the standard blood checks on admission or in early stage. In this study we investigated if a rapid assay of interleukin (IL)-6 is useful in influenza-associated encephalopathy in early stages. The levels of IL-6 in patients with influenza-associated encephalopathy did not show any significant difference compared with those in patients with febrile convulsion and rotavirus-associated convulsion. However the levels of IL-6 in severe cases were significantly higher than those of mild cases with influenza-associated encephalopathy. Consequently the rapid assay of serum IL-6 is useful to evaluate and decide the therapies. IOS Press 2005 2006-01-05 /pmc/articles/PMC3851426/ /pubmed/16403955 http://dx.doi.org/10.1155/2005/671609 Text en Copyright © 2005 Hindawi Publishing Corporation.
spellingShingle Other
Nakamura, Mikage
Yamanaka, Gaku
Kawashima, Hisashi
Watanabe, Yoshiaki
Ioi, Hiroaki
Kashiwagi, Yasuyo
Takekuma, Kouji
Hoshika, Akinori
Hayakawa, Mizuho
Suzuki, Shigeru
Clinical Application of Rapid Assay of Interleukin-6 in Influenza-Associated Encephalopathy
title Clinical Application of Rapid Assay of Interleukin-6 in Influenza-Associated Encephalopathy
title_full Clinical Application of Rapid Assay of Interleukin-6 in Influenza-Associated Encephalopathy
title_fullStr Clinical Application of Rapid Assay of Interleukin-6 in Influenza-Associated Encephalopathy
title_full_unstemmed Clinical Application of Rapid Assay of Interleukin-6 in Influenza-Associated Encephalopathy
title_short Clinical Application of Rapid Assay of Interleukin-6 in Influenza-Associated Encephalopathy
title_sort clinical application of rapid assay of interleukin-6 in influenza-associated encephalopathy
topic Other
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851426/
https://www.ncbi.nlm.nih.gov/pubmed/16403955
http://dx.doi.org/10.1155/2005/671609
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