Novel HCN2 Mutation Contributes to Febrile Seizures by Shifting the Channel's Kinetics in a Temperature-Dependent Manner

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channel-mediated currents, known as I (h), are involved in the control of rhythmic activity in neuronal circuits and in determining neuronal properties including the resting membrane potential. Recent studies have shown that HCN channels play...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakamura, Yuki, Shi, Xiuyu, Numata, Tomohiro, Mori, Yasuo, Inoue, Ryuji, Lossin, Christoph, Baram, Tallie Z., Hirose, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851455/
https://www.ncbi.nlm.nih.gov/pubmed/24324597
http://dx.doi.org/10.1371/journal.pone.0080376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851455/
https://www.ncbi.nlm.nih.gov/pubmed/24324597
http://dx.doi.org/10.1371/journal.pone.0080376

Ejemplares similares