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Novel HCN2 Mutation Contributes to Febrile Seizures by Shifting the Channel's Kinetics in a Temperature-Dependent Manner
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channel-mediated currents, known as I (h), are involved in the control of rhythmic activity in neuronal circuits and in determining neuronal properties including the resting membrane potential. Recent studies have shown that HCN channels play...
Autores principales: | Nakamura, Yuki, Shi, Xiuyu, Numata, Tomohiro, Mori, Yasuo, Inoue, Ryuji, Lossin, Christoph, Baram, Tallie Z., Hirose, Shinichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851455/ https://www.ncbi.nlm.nih.gov/pubmed/24324597 http://dx.doi.org/10.1371/journal.pone.0080376 |
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