Cargando…

PMS: A Panoptic Motif Search Tool

BACKGROUND: Identification of DNA/Protein motifs is a crucial problem for biologists. Computational techniques could be of great help in this identification. In this direction, many computational models for motifs have been proposed in the literature. METHODS: One such important model is the [Image:...

Descripción completa

Detalles Bibliográficos
Autores principales: Dinh, Hieu, Rajasekaran, Sanguthevar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851466/
https://www.ncbi.nlm.nih.gov/pubmed/24324619
http://dx.doi.org/10.1371/journal.pone.0080660
Descripción
Sumario:BACKGROUND: Identification of DNA/Protein motifs is a crucial problem for biologists. Computational techniques could be of great help in this identification. In this direction, many computational models for motifs have been proposed in the literature. METHODS: One such important model is the [Image: see text] motif model. In this paper we describe a motif search web tool that predominantly employs this motif model. This web tool exploits the state-of-the art algorithms for solving the [Image: see text] motif search problem. RESULTS: The online tool has been helping scientists identify many unknown motifs. Many of our predictions have been successfully verified as well. We hope that this paper will expose this crucial tool to many more scientists. AVAILABILITY AND REQUIREMENTS: Project name: PMS - Panoptic Motif Search Tool. Project home page: http://pms.engr.uconn.edu or http://motifsearch.com. Licence: PMS tools will be readily available to any scientist wishing to use it for non-commercial purposes, without restrictions. The online tool is freely available without login.