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PMS: A Panoptic Motif Search Tool
BACKGROUND: Identification of DNA/Protein motifs is a crucial problem for biologists. Computational techniques could be of great help in this identification. In this direction, many computational models for motifs have been proposed in the literature. METHODS: One such important model is the [Image:...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851466/ https://www.ncbi.nlm.nih.gov/pubmed/24324619 http://dx.doi.org/10.1371/journal.pone.0080660 |
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author | Dinh, Hieu Rajasekaran, Sanguthevar |
author_facet | Dinh, Hieu Rajasekaran, Sanguthevar |
author_sort | Dinh, Hieu |
collection | PubMed |
description | BACKGROUND: Identification of DNA/Protein motifs is a crucial problem for biologists. Computational techniques could be of great help in this identification. In this direction, many computational models for motifs have been proposed in the literature. METHODS: One such important model is the [Image: see text] motif model. In this paper we describe a motif search web tool that predominantly employs this motif model. This web tool exploits the state-of-the art algorithms for solving the [Image: see text] motif search problem. RESULTS: The online tool has been helping scientists identify many unknown motifs. Many of our predictions have been successfully verified as well. We hope that this paper will expose this crucial tool to many more scientists. AVAILABILITY AND REQUIREMENTS: Project name: PMS - Panoptic Motif Search Tool. Project home page: http://pms.engr.uconn.edu or http://motifsearch.com. Licence: PMS tools will be readily available to any scientist wishing to use it for non-commercial purposes, without restrictions. The online tool is freely available without login. |
format | Online Article Text |
id | pubmed-3851466 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-38514662013-12-09 PMS: A Panoptic Motif Search Tool Dinh, Hieu Rajasekaran, Sanguthevar PLoS One Research Article BACKGROUND: Identification of DNA/Protein motifs is a crucial problem for biologists. Computational techniques could be of great help in this identification. In this direction, many computational models for motifs have been proposed in the literature. METHODS: One such important model is the [Image: see text] motif model. In this paper we describe a motif search web tool that predominantly employs this motif model. This web tool exploits the state-of-the art algorithms for solving the [Image: see text] motif search problem. RESULTS: The online tool has been helping scientists identify many unknown motifs. Many of our predictions have been successfully verified as well. We hope that this paper will expose this crucial tool to many more scientists. AVAILABILITY AND REQUIREMENTS: Project name: PMS - Panoptic Motif Search Tool. Project home page: http://pms.engr.uconn.edu or http://motifsearch.com. Licence: PMS tools will be readily available to any scientist wishing to use it for non-commercial purposes, without restrictions. The online tool is freely available without login. Public Library of Science 2013-12-04 /pmc/articles/PMC3851466/ /pubmed/24324619 http://dx.doi.org/10.1371/journal.pone.0080660 Text en © 2013 Dinh, Rajasekaran http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Dinh, Hieu Rajasekaran, Sanguthevar PMS: A Panoptic Motif Search Tool |
title | PMS: A Panoptic Motif Search Tool |
title_full | PMS: A Panoptic Motif Search Tool |
title_fullStr | PMS: A Panoptic Motif Search Tool |
title_full_unstemmed | PMS: A Panoptic Motif Search Tool |
title_short | PMS: A Panoptic Motif Search Tool |
title_sort | pms: a panoptic motif search tool |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851466/ https://www.ncbi.nlm.nih.gov/pubmed/24324619 http://dx.doi.org/10.1371/journal.pone.0080660 |
work_keys_str_mv | AT dinhhieu pmsapanopticmotifsearchtool AT rajasekaransanguthevar pmsapanopticmotifsearchtool |