Cargando…

PMS: A Panoptic Motif Search Tool

BACKGROUND: Identification of DNA/Protein motifs is a crucial problem for biologists. Computational techniques could be of great help in this identification. In this direction, many computational models for motifs have been proposed in the literature. METHODS: One such important model is the [Image:...

Descripción completa

Detalles Bibliográficos
Autores principales: Dinh, Hieu, Rajasekaran, Sanguthevar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851466/
https://www.ncbi.nlm.nih.gov/pubmed/24324619
http://dx.doi.org/10.1371/journal.pone.0080660
_version_ 1782294289512923136
author Dinh, Hieu
Rajasekaran, Sanguthevar
author_facet Dinh, Hieu
Rajasekaran, Sanguthevar
author_sort Dinh, Hieu
collection PubMed
description BACKGROUND: Identification of DNA/Protein motifs is a crucial problem for biologists. Computational techniques could be of great help in this identification. In this direction, many computational models for motifs have been proposed in the literature. METHODS: One such important model is the [Image: see text] motif model. In this paper we describe a motif search web tool that predominantly employs this motif model. This web tool exploits the state-of-the art algorithms for solving the [Image: see text] motif search problem. RESULTS: The online tool has been helping scientists identify many unknown motifs. Many of our predictions have been successfully verified as well. We hope that this paper will expose this crucial tool to many more scientists. AVAILABILITY AND REQUIREMENTS: Project name: PMS - Panoptic Motif Search Tool. Project home page: http://pms.engr.uconn.edu or http://motifsearch.com. Licence: PMS tools will be readily available to any scientist wishing to use it for non-commercial purposes, without restrictions. The online tool is freely available without login.
format Online
Article
Text
id pubmed-3851466
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-38514662013-12-09 PMS: A Panoptic Motif Search Tool Dinh, Hieu Rajasekaran, Sanguthevar PLoS One Research Article BACKGROUND: Identification of DNA/Protein motifs is a crucial problem for biologists. Computational techniques could be of great help in this identification. In this direction, many computational models for motifs have been proposed in the literature. METHODS: One such important model is the [Image: see text] motif model. In this paper we describe a motif search web tool that predominantly employs this motif model. This web tool exploits the state-of-the art algorithms for solving the [Image: see text] motif search problem. RESULTS: The online tool has been helping scientists identify many unknown motifs. Many of our predictions have been successfully verified as well. We hope that this paper will expose this crucial tool to many more scientists. AVAILABILITY AND REQUIREMENTS: Project name: PMS - Panoptic Motif Search Tool. Project home page: http://pms.engr.uconn.edu or http://motifsearch.com. Licence: PMS tools will be readily available to any scientist wishing to use it for non-commercial purposes, without restrictions. The online tool is freely available without login. Public Library of Science 2013-12-04 /pmc/articles/PMC3851466/ /pubmed/24324619 http://dx.doi.org/10.1371/journal.pone.0080660 Text en © 2013 Dinh, Rajasekaran http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Dinh, Hieu
Rajasekaran, Sanguthevar
PMS: A Panoptic Motif Search Tool
title PMS: A Panoptic Motif Search Tool
title_full PMS: A Panoptic Motif Search Tool
title_fullStr PMS: A Panoptic Motif Search Tool
title_full_unstemmed PMS: A Panoptic Motif Search Tool
title_short PMS: A Panoptic Motif Search Tool
title_sort pms: a panoptic motif search tool
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851466/
https://www.ncbi.nlm.nih.gov/pubmed/24324619
http://dx.doi.org/10.1371/journal.pone.0080660
work_keys_str_mv AT dinhhieu pmsapanopticmotifsearchtool
AT rajasekaransanguthevar pmsapanopticmotifsearchtool