Homology modeling, molecular docking, and molecular dynamics simulations elucidated α-fetoprotein binding modes

BACKGROUND: An important mechanism of endocrine activity is chemicals entering target cells via transport proteins and then interacting with hormone receptors such as the estrogen receptor (ER). α-Fetoprotein (AFP) is a major transport protein in rodent serum that can bind and sequester estrogens, t...

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Detalles Bibliográficos
Autores principales: Shen, Jie, Zhang, Wenqian, Fang, Hong, Perkins, Roger, Tong, Weida, Hong, Huixiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851483/
https://www.ncbi.nlm.nih.gov/pubmed/24266910
http://dx.doi.org/10.1186/1471-2105-14-S14-S6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851483/
https://www.ncbi.nlm.nih.gov/pubmed/24266910
http://dx.doi.org/10.1186/1471-2105-14-S14-S6

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