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Age-dependent effects of microglial inhibition in vivo on Alzheimer’s disease neuropathology using bioactive-conjugated iron oxide nanoparticles
BACKGROUND: Tau dysfunction is believed to be the primary cause of neurodegenerative disorders referred to as tauopathies, including Alzheimer’s disease, Pick’s disease, frontotemporal dementia and Parkinsonism. The role of microglial cells in the pathogenesis of tauopathies is still unclear. The ac...
Autores principales: | Glat, Micaela, Skaat, Hadas, Menkes-Caspi, Noa, Margel, Shlomo, Stern, Edward A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851539/ https://www.ncbi.nlm.nih.gov/pubmed/24059692 http://dx.doi.org/10.1186/1477-3155-11-32 |
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