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A recombinant pseudotyped lentivirus expressing the envelope glycoprotein of Hantaan virus induced protective immunity in mice

BACKGROUND: Hantaviruses cause acute hemorrhagic fever with renal syndrome (HFRS). Currently, several types of inactivated HFRS vaccines are widely used, however the limited ability of these immunogen to elicit neutralizing antibodies restricts vaccine efficacy. Development of an effective vaccine t...

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Detalles Bibliográficos
Autores principales: Yu, Lan, Bai, Wentao, Wu, Xingan, Zhang, Liang, Zhang, Lei, Li, Puyuan, Wang, Fang, Liu, Ziyu, Zhang, Fanglin, Xu, Zhikai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851560/
https://www.ncbi.nlm.nih.gov/pubmed/24093752
http://dx.doi.org/10.1186/1743-422X-10-301