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No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial

BACKGROUND AND PURPOSE: Hydroxyapatite (HA) coating is believed to improve bone-implant ingrowth and long-term survival of prostheses. Recent studies, however, have challenged this view. Furthermore, HA particles may produce third-body wear and initiate aseptic loosening of implants. We report the p...

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Autores principales: Valancius, Kestutis, Søballe, Kjeld, Nielsen, Poul T, Laursen, Mogens B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851667/
https://www.ncbi.nlm.nih.gov/pubmed/24171680
http://dx.doi.org/10.3109/17453674.2013.854665
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author Valancius, Kestutis
Søballe, Kjeld
Nielsen, Poul T
Laursen, Mogens B
author_facet Valancius, Kestutis
Søballe, Kjeld
Nielsen, Poul T
Laursen, Mogens B
author_sort Valancius, Kestutis
collection PubMed
description BACKGROUND AND PURPOSE: Hydroxyapatite (HA) coating is believed to improve bone-implant ingrowth and long-term survival of prostheses. Recent studies, however, have challenged this view. Furthermore, HA particles may produce third-body wear and initiate aseptic loosening of implants. We report the performance of HA- and porous-coated acetabular cups in a prospective randomized trial. METHODS: This was an 8-year follow-up study of our previously published prospective randomized study to compare clinical outcomes, survival, periprosthetic bone mineral density, migration, and wear rates of HA- and porous-coated acetabular cups. Dual X-ray absorptiometry (DXA) and Ein Bild Roentgen Analyse (EBRA) measurements were used. 100 patients who underwent unilateral cementless total hip arthroplasty were randomized to either porous-coated cups or HA-coated cups. Patients were examined preoperatively and at 3, 6, and 9 months, and also 1, 3, and 8 years after surgery. 81 patients were available for 8-year follow-up, 40 with porous-coated cups and 41 with HA-coated cups. RESULTS: Age, sex, bone mineral density, and clinical results (Harris hip score) were similar in the 2 groups. The survival, wear, and migration patterns of the cups were also similar in both groups. The results of periprosthetic bone mineral density scans in region of interest 2 was in favor of the porous-coated cups, but there were no differences between the 2 groups in all the remaining regions of interest. INTERPRETATION: HA coating had no statistically significant effect on clinical results, survival, wear, or migration at the 8-year follow-up.
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spelling pubmed-38516672013-12-08 No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial Valancius, Kestutis Søballe, Kjeld Nielsen, Poul T Laursen, Mogens B Acta Orthop Article BACKGROUND AND PURPOSE: Hydroxyapatite (HA) coating is believed to improve bone-implant ingrowth and long-term survival of prostheses. Recent studies, however, have challenged this view. Furthermore, HA particles may produce third-body wear and initiate aseptic loosening of implants. We report the performance of HA- and porous-coated acetabular cups in a prospective randomized trial. METHODS: This was an 8-year follow-up study of our previously published prospective randomized study to compare clinical outcomes, survival, periprosthetic bone mineral density, migration, and wear rates of HA- and porous-coated acetabular cups. Dual X-ray absorptiometry (DXA) and Ein Bild Roentgen Analyse (EBRA) measurements were used. 100 patients who underwent unilateral cementless total hip arthroplasty were randomized to either porous-coated cups or HA-coated cups. Patients were examined preoperatively and at 3, 6, and 9 months, and also 1, 3, and 8 years after surgery. 81 patients were available for 8-year follow-up, 40 with porous-coated cups and 41 with HA-coated cups. RESULTS: Age, sex, bone mineral density, and clinical results (Harris hip score) were similar in the 2 groups. The survival, wear, and migration patterns of the cups were also similar in both groups. The results of periprosthetic bone mineral density scans in region of interest 2 was in favor of the porous-coated cups, but there were no differences between the 2 groups in all the remaining regions of interest. INTERPRETATION: HA coating had no statistically significant effect on clinical results, survival, wear, or migration at the 8-year follow-up. Informa Healthcare 2013-12 2013-12-02 /pmc/articles/PMC3851667/ /pubmed/24171680 http://dx.doi.org/10.3109/17453674.2013.854665 Text en Copyright: © Nordic Orthopaedic Federation http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the source is credited.
spellingShingle Article
Valancius, Kestutis
Søballe, Kjeld
Nielsen, Poul T
Laursen, Mogens B
No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial
title No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial
title_full No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial
title_fullStr No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial
title_full_unstemmed No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial
title_short No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial
title_sort no superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: an 8-year follow-up of 81 patients from a previously reported controlled trial
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851667/
https://www.ncbi.nlm.nih.gov/pubmed/24171680
http://dx.doi.org/10.3109/17453674.2013.854665
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