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No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial
BACKGROUND AND PURPOSE: Hydroxyapatite (HA) coating is believed to improve bone-implant ingrowth and long-term survival of prostheses. Recent studies, however, have challenged this view. Furthermore, HA particles may produce third-body wear and initiate aseptic loosening of implants. We report the p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851667/ https://www.ncbi.nlm.nih.gov/pubmed/24171680 http://dx.doi.org/10.3109/17453674.2013.854665 |
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author | Valancius, Kestutis Søballe, Kjeld Nielsen, Poul T Laursen, Mogens B |
author_facet | Valancius, Kestutis Søballe, Kjeld Nielsen, Poul T Laursen, Mogens B |
author_sort | Valancius, Kestutis |
collection | PubMed |
description | BACKGROUND AND PURPOSE: Hydroxyapatite (HA) coating is believed to improve bone-implant ingrowth and long-term survival of prostheses. Recent studies, however, have challenged this view. Furthermore, HA particles may produce third-body wear and initiate aseptic loosening of implants. We report the performance of HA- and porous-coated acetabular cups in a prospective randomized trial. METHODS: This was an 8-year follow-up study of our previously published prospective randomized study to compare clinical outcomes, survival, periprosthetic bone mineral density, migration, and wear rates of HA- and porous-coated acetabular cups. Dual X-ray absorptiometry (DXA) and Ein Bild Roentgen Analyse (EBRA) measurements were used. 100 patients who underwent unilateral cementless total hip arthroplasty were randomized to either porous-coated cups or HA-coated cups. Patients were examined preoperatively and at 3, 6, and 9 months, and also 1, 3, and 8 years after surgery. 81 patients were available for 8-year follow-up, 40 with porous-coated cups and 41 with HA-coated cups. RESULTS: Age, sex, bone mineral density, and clinical results (Harris hip score) were similar in the 2 groups. The survival, wear, and migration patterns of the cups were also similar in both groups. The results of periprosthetic bone mineral density scans in region of interest 2 was in favor of the porous-coated cups, but there were no differences between the 2 groups in all the remaining regions of interest. INTERPRETATION: HA coating had no statistically significant effect on clinical results, survival, wear, or migration at the 8-year follow-up. |
format | Online Article Text |
id | pubmed-3851667 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Informa Healthcare |
record_format | MEDLINE/PubMed |
spelling | pubmed-38516672013-12-08 No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial Valancius, Kestutis Søballe, Kjeld Nielsen, Poul T Laursen, Mogens B Acta Orthop Article BACKGROUND AND PURPOSE: Hydroxyapatite (HA) coating is believed to improve bone-implant ingrowth and long-term survival of prostheses. Recent studies, however, have challenged this view. Furthermore, HA particles may produce third-body wear and initiate aseptic loosening of implants. We report the performance of HA- and porous-coated acetabular cups in a prospective randomized trial. METHODS: This was an 8-year follow-up study of our previously published prospective randomized study to compare clinical outcomes, survival, periprosthetic bone mineral density, migration, and wear rates of HA- and porous-coated acetabular cups. Dual X-ray absorptiometry (DXA) and Ein Bild Roentgen Analyse (EBRA) measurements were used. 100 patients who underwent unilateral cementless total hip arthroplasty were randomized to either porous-coated cups or HA-coated cups. Patients were examined preoperatively and at 3, 6, and 9 months, and also 1, 3, and 8 years after surgery. 81 patients were available for 8-year follow-up, 40 with porous-coated cups and 41 with HA-coated cups. RESULTS: Age, sex, bone mineral density, and clinical results (Harris hip score) were similar in the 2 groups. The survival, wear, and migration patterns of the cups were also similar in both groups. The results of periprosthetic bone mineral density scans in region of interest 2 was in favor of the porous-coated cups, but there were no differences between the 2 groups in all the remaining regions of interest. INTERPRETATION: HA coating had no statistically significant effect on clinical results, survival, wear, or migration at the 8-year follow-up. Informa Healthcare 2013-12 2013-12-02 /pmc/articles/PMC3851667/ /pubmed/24171680 http://dx.doi.org/10.3109/17453674.2013.854665 Text en Copyright: © Nordic Orthopaedic Federation http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the source is credited. |
spellingShingle | Article Valancius, Kestutis Søballe, Kjeld Nielsen, Poul T Laursen, Mogens B No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial |
title | No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial |
title_full | No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial |
title_fullStr | No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial |
title_full_unstemmed | No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial |
title_short | No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial |
title_sort | no superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: an 8-year follow-up of 81 patients from a previously reported controlled trial |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851667/ https://www.ncbi.nlm.nih.gov/pubmed/24171680 http://dx.doi.org/10.3109/17453674.2013.854665 |
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