MicroRNAs as the cause of schizophrenia in 22q11.2 deletion carriers, and possible implications for idiopathic disease: a mini-review

The 22q11.2 deletion is the strongest known genetic risk factor for schizophrenia. Research has implicated microRNA-mediated dysregulation in 22q11.2 deletion syndrome (22q11.2DS) schizophrenia-risk. Primary candidate genes are DGCR8 (DiGeorge syndrome critical region gene 8), which encodes a compon...

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Detalles Bibliográficos
Autores principales: Forstner, Andreas J., Degenhardt, Franziska, Schratt, Gerhard, Nöthen, Markus M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851736/
https://www.ncbi.nlm.nih.gov/pubmed/24367288
http://dx.doi.org/10.3389/fnmol.2013.00047

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