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Mahanine restores RASSF1A expression by down-regulating DNMT1 and DNMT3B in prostate cancer cells

BACKGROUND: Hypermethylation of the promoter of the tumor suppressor gene RASSF1A silences its expression and has been found to be associated with advanced grade prostatic tumors. The DNA methyltransferase (DNMT) family of enzymes are known to be involved in the epigenetic silencing of gene expressi...

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Detalles Bibliográficos
Autores principales:	Agarwal, Soumik, Amin, Karishma S, Jagadeesh, Shankar, Baishay, Gokul, Rao, Paruchuri G, Barua, Nabin C, Bhattacharya, Samir, Banerjee, Partha P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851847/ https://www.ncbi.nlm.nih.gov/pubmed/24001151 http://dx.doi.org/10.1186/1476-4598-12-99

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