A transient reversal of miRNA-mediated repression controls macrophage activation

In mammalian macrophages, the expression of a number of cytokines is regulated by miRNAs. Upon macrophage activation, proinflammatory cytokine mRNAs are translated, although the expression of miRNAs targeting these mRNAs remains largely unaltered. We show that there is a transient reversal of miRNA-...

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Detalles Bibliográficos
Autores principales: Mazumder, Anup, Bose, Mainak, Chakraborty, Abhijit, Chakrabarti, Saikat, Bhattacharyya, Suvendra N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Scientific Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851954/
https://www.ncbi.nlm.nih.gov/pubmed/24030283
http://dx.doi.org/10.1038/embor.2013.149

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