Cargando…
The role of PD-1 and PD-L1 in T-cell immune suppression in patients with hematological malignancies
T-cell activation and dysfunction relies on direct and modulated receptors. Based on their functional outcome, co-signaling molecules can be divided as co-stimulators and co-inhibitors, which positively and negatively control the priming, growth, differentiation and functional maturation of a T-cell...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851976/ https://www.ncbi.nlm.nih.gov/pubmed/24283718 http://dx.doi.org/10.1186/1756-8722-6-74 |