Prognostic significance and therapeutic potential of the activation of anaplastic lymphoma kinase/protein kinase B/mammalian target of rapamycin signaling pathway in anaplastic large cell lymphoma

BACKGROUD: Activation of the protein kinase B/mammalian target of rapamycin (AKT/mTOR) pathway has been demonstrated to be involved in nucleophosmin-anaplastic lymphoma kinase (NPM-ALK)-mediated tumorigenesis in anaplastic large cell lymphoma (ALCL) and correlated with unfavorable outcome in certain...

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Detalles Bibliográficos
Autores principales: Gao, Ju, Yin, Minzhi, Zhu, Yiping, Gu, Ling, Zhang, Yanle, Li, Qiang, Jia, Cangsong, Ma, Zhigui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852000/
https://www.ncbi.nlm.nih.gov/pubmed/24112608
http://dx.doi.org/10.1186/1471-2407-13-471

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