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Canonical Wnt/β-Catenin Signalling Is Essential for Optic Cup Formation
A multitude of signalling pathways are involved in the process of forming an eye. Here we demonstrate that β-catenin is essential for eye development as inactivation of β-catenin prior to cellular specification in the optic vesicle caused anophthalmia in mice. By achieving this early and tissue-spec...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852023/ https://www.ncbi.nlm.nih.gov/pubmed/24324671 http://dx.doi.org/10.1371/journal.pone.0081158 |