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Mapping proteins in the presence of paralogs using units of coevolution

BACKGROUND: We study the problem of mapping proteins between two protein families in the presence of paralogs. This problem occurs as a difficult subproblem in coevolution-based computational approaches for protein-protein interaction prediction. RESULTS: Similar to prior approaches, our method is b...

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Detalles Bibliográficos
Autores principales: El-Kebir, Mohammed, Marschall, Tobias, Wohlers, Inken, Patterson, Murray, Heringa, Jaap, Schönhuth, Alexander, Klau, Gunnar W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852051/
https://www.ncbi.nlm.nih.gov/pubmed/24564758
http://dx.doi.org/10.1186/1471-2105-14-S15-S18