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FOXO/TXNIP pathway is involved in the suppression of hepatocellular carcinoma growth by glutamate antagonist MK-801

BACKGROUND: Accumulating evidence has suggested the importance of glutamate signaling in cancer growth, yet the signaling pathway has not been fully elucidated. N-methyl-D-aspartic acid (NMDA) receptor activates intracellular signaling pathways such as the extracellular-signal-regulated kinase (ERK)...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Fuminori, Hirata, Yuko, Akram, Hossain, Kamitori, Kazuyo, Dong, Youyi, Sui, Li, Tokuda, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852080/
https://www.ncbi.nlm.nih.gov/pubmed/24112473
http://dx.doi.org/10.1186/1471-2407-13-468