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E. coli Endotoxin Modulates the Expression of Sirtuin Proteins in PBMC in Humans

Background. Sirtuin (SIRT) proteins are class I histone deacetylases displaying gene regulatory functions in inflammatory, cancer, and metabolic diseases. These SIRT actions involve the nuclear factor κB and its inhibitor IκB pathway. However, the regulation of SIRT in vivo is still unclear. Materia...

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Detalles Bibliográficos
Autores principales: Storka, Angela, Führlinger, Gerhard, Seper, Martin, Wang, Lisa, Jew, Michael, Leisser, Asha, Wolzt, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852091/
https://www.ncbi.nlm.nih.gov/pubmed/24347837
http://dx.doi.org/10.1155/2013/876943