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The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter (MCU)
Mitochondrial calcium has been postulated to regulate a wide range of processes from bioenergetics to cell death. Here, we characterize a mouse model that lacks expression of the recently discovered mitochondrial calcium uniporter (MCU). Mitochondria derived from MCU(-/-) mice have no apparent capac...
Autores principales: | Pan, Xin, Liu, Jie, Nguyen, Tiffany, Liu, Chengyu, Sun, Junhui, Teng, Yanjie, Fergusson, Maria M, Rovira, Ilsa I, Allen, Michele, Springer, Danielle A., Aponte, Angel M., Gucek, Marjan, Balaban, Robert S., Murphy, Elizabeth, Finkel, Toren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852190/ https://www.ncbi.nlm.nih.gov/pubmed/24212091 http://dx.doi.org/10.1038/ncb2868 |
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