Cargando…

The Mediator complex and transcription regulation

The Mediator complex is a multi-subunit assembly that appears to be required for regulating expression of most RNA polymerase II (pol II) transcripts, which include protein-coding and most non-coding RNA genes. Mediator and pol II function within the pre-initiation complex (PIC), which consists of M...

Descripción completa

Detalles Bibliográficos
Autores principales:	Poss, Zachary C., Ebmeier, Christopher C., Taatjes, Dylan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Informa Healthcare USA, Inc. 2013
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852498/ https://www.ncbi.nlm.nih.gov/pubmed/24088064 http://dx.doi.org/10.3109/10409238.2013.840259

Ejemplares similares

CDK8 is a positive regulator of transcriptional elongation within the serum response network
por: Donner, Aaron J., et al.
Publicado: (2010)

The Mediator complex as a master regulator of transcription by RNA polymerase II
por: Richter, William F., et al.
Publicado: (2022)

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair
por: Guard, Steven E., et al.
Publicado: (2019)

Molecular Architecture of the Human Mediator–RNA Polymerase II–TFIIF Assembly
por: Bernecky, Carrie, et al.
Publicado: (2011)

CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response
por: Bancerek, Joanna, et al.
Publicado: (2013)

Structure and mechanism of the RNA polymerase II transcription machinery
por: Schier, Allison C., et al.
Publicado: (2020)

The complex structure and function of Mediator
por: Harper, Thomas M., et al.
Publicado: (2018)

The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy
por: Sewell, Aileen K., et al.
Publicado: (2022)

The essential and multifunctional TFIIH complex
por: Rimel, Jenna K., et al.
Publicado: (2018)

Regulatory functions of the Mediator kinases CDK8 and CDK19
por: Fant, Charli B., et al.
Publicado: (2018)

p53 activates transcription by directing structural shifts within Mediator
por: Meyer, Krista D., et al.
Publicado: (2010)

TRIM28 regulates RNA polymerase II promoter proximal pausing and pause release
por: Bunch, Heeyoun, et al.
Publicado: (2014)

Activating RNAs associate with Mediator to enhance chromatin architecture and transcription
por: Lai, Fan, et al.
Publicado: (2013)

Structural visualization of key steps in human transcription initiation
por: He, Yuan, et al.
Publicado: (2013)

Mediator and Cohesin Connect Gene Expression and Chromatin Architecture
por: Kagey, Michael H., et al.
Publicado: (2010)

The Δ40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription factors during p53 activation
por: Levandowski, Cecilia B., et al.
Publicado: (2021)

Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment
por: Rubin, Jonathan D., et al.
Publicado: (2021)

Malleable Machines in Transcription Regulation: The Mediator Complex
por: Tóth-Petróczy, Ágnes, et al.
Publicado: (2008)

Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription
por: Rimel, Jenna K., et al.
Publicado: (2020)

Mediator Kinase Inhibition Further Activates Super-Enhancer Associated Genes in AML
por: Pelish, Henry E., et al.
Publicado: (2015)

Systematic mutagenesis of TFIIH subunit p52/Tfb2 identifies residues required for XPB/Ssl2 subunit function and genetic interactions with TFB6
por: Bassett, Jacob, et al.
Publicado: (2022)

ΔNp53 and aging
por: Lin, Shih-Chieh, et al.
Publicado: (2013)

Regulation of metabolism by the Mediator complex
por: Youn, Dou Yeon, et al.
Publicado: (2016)

A complex network of transcription factors and epigenetic regulators involved in bovine leukemia virus transcriptional regulation
por: Plant, Estelle, et al.
Publicado: (2023)

The Histochem Cell Biol conspectus: the year 2013 in review
por: Taatjes, Douglas J., et al.
Publicado: (2014)

Histochemistry and Cell Biology—a glance into the past and a look ahead
por: Roth, Jürgen, et al.
Publicado: (2023)

Morphological and cytochemical determination of cell death by apoptosis
por: Taatjes, Douglas J., et al.
Publicado: (2007)

Transcription complexes as RNA chaperones
por: Said, Nelly, et al.
Publicado: (2021)

Structures of transcription pre-initiation complex with TFIIH and Mediator
por: Schilbach, S., et al.
Publicado: (2017)

The transcription regulator ATF4 is a mediator of skeletal muscle aging
por: Miller, Matthew J., et al.
Publicado: (2023)

Mediator Kinase Inhibition Impedes Transcriptional Plasticity and Prevents Resistance to ERK/MAPK-Targeted Therapy in KRAS-Mutant Cancers
por: Wood, Kris, et al.
Publicado: (2023)

Dia2 Controls Transcription by Mediating Assembly of the RSC Complex
por: Andress, Edward J., et al.
Publicado: (2011)

BET Protein-Mediated Transcriptional Regulation in Heart Failure
por: Ijaz, Talha, et al.
Publicado: (2021)

Pol II phosphorylation regulates a switch between transcriptional and splicing condensates
por: Guo, Yang Eric, et al.
Publicado: (2019)

Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes
por: Raab, Jesse R., et al.
Publicado: (2015)

Complexities of post-transcriptional regulation and the modeling of ceRNA crosstalk
por: Smillie, Claire L., et al.
Publicado: (2018)

Trans-tail regulation-mediated suppression of cryptic transcription
por: Choi, Jungmin, et al.
Publicado: (2021)

Interleukin-Mediated Pendrin Transcriptional Regulation in Airway and Esophageal Epithelia
por: Vanoni, Simone, et al.
Publicado: (2019)

Exploring the Role of Enhancer-Mediated Transcriptional Regulation in Precision Biology
por: Wang, Xueyan, et al.
Publicado: (2023)

Transcriptional regulation of protein complexes in yeast
por: Simonis, Nicolas, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_if23fl3a923jh94hu94i49ivan