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Lack of RNase L Attenuates Macrophage Functions

BACKGROUND: Macrophages are one of the major cell types in innate immunity against microbial infection. It is believed that the expression of proinflammatory genes such as tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL–6, and cyclooxygenase-2 (Cox-2) by macrophages is also crucial for acti...

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Detalles Bibliográficos
Autores principales: Yi, Xin, Zeng, Chun, Liu, Hongli, Chen, Xiaoli, Zhang, Ping, Yun, Boo Seok, Jin, Ge, Zhou, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852499/
https://www.ncbi.nlm.nih.gov/pubmed/24324683
http://dx.doi.org/10.1371/journal.pone.0081269

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