Cargando…

Chronic Intermittent Hypoxia Exerts CNS Region-Specific Effects on Rat Microglial Inflammatory and TLR4 Gene Expression

Intermittent hypoxia (IH) during sleep is a hallmark of sleep apnea, causing significant neuronal apoptosis, and cognitive and behavioral deficits in CNS regions underlying memory processing and executive functions. IH-induced neuroinflammation is thought to contribute to cognitive deficits after IH...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smith, Stephanie M. C., Friedle, Scott A., Watters, Jyoti J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852519/ https://www.ncbi.nlm.nih.gov/pubmed/24324707 http://dx.doi.org/10.1371/journal.pone.0081584

Ejemplares similares

Neonatal Intermittent Hypoxia Induces Lasting Sex-Specific Augmentation of Rat Microglial Cytokine Expression
por: Kiernan, Elizabeth A., et al.
Publicado: (2019)

Hypoxia attenuates purinergic P2X receptor-induced inflammatory gene expression in brainstem microglia
por: Smith, Stephanie MC, et al.
Publicado: (2013)

Cell-type-specific Jumonji histone demethylase gene expression in the healthy rat CNS: detection by a novel flow cytometry method
por: Smith, Stephanie M.C., et al.
Publicado: (2014)

TLR4 mediates inflammation and hepatic fibrosis induced by chronic intermittent hypoxia in rats
por: Lin, Zhi-Peng, et al.
Publicado: (2020)

TLR4 mediates inflammation and hepatic fibrosis induced by chronic intermittent hypoxia in rats
por: Lin, Zhi-Peng, et al.
Publicado: (2021)

Prior Hypoxia Exposure Enhances Murine Microglial Inflammatory Gene Expression in vitro Without Concomitant H3K4me3 Enrichment
por: Kiernan, Elizabeth A., et al.
Publicado: (2020)

Contribution of TLR4 signaling in intermittent hypoxia-mediated atherosclerosis progression
por: Zeng, Xianqin, et al.
Publicado: (2018)

Microglial exosomes alleviate intermittent hypoxia-induced cognitive deficits by suppressing NLRP3 inflammasome
por: Zhang, Yaodan, et al.
Publicado: (2023)

Are Microglial Cells the Regulators of Lymphocyte Responses in the CNS?
por: Almolda, Beatriz, et al.
Publicado: (2015)

Atmospheric particulate matter aggravates CNS demyelination through involvement of TLR-4/NF-kB signaling and microglial activation
por: Han, Bing, et al.
Publicado: (2022)

Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia
por: Yao, Linli, et al.
Publicado: (2013)

Microglial aging in the healthy CNS: phenotypes, drivers, and rejuvenation
por: Wong, Wai T.
Publicado: (2013)

Microglial Phagocytosis of Neurons: Diminishing Neuronal Loss in Traumatic, Infectious, Inflammatory, and Autoimmune CNS Disorders
por: Yanuck, Samuel F.
Publicado: (2019)

CNS changes in chronic hypoxia
por: Aguilar N, NM, et al.
Publicado: (2001)

Sweepers in the CNS: Microglial Migration and Phagocytosis in the Alzheimer Disease Pathogenesis
por: Noda, Mariko, et al.
Publicado: (2012)

Regulation of Microglial Functions by Purinergic Mechanisms in the Healthy and Diseased CNS
por: Illes, Peter, et al.
Publicado: (2020)

Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands
por: Das, Amitabh, et al.
Publicado: (2015)

Microglial activation by microbial neuraminidase through TLR2 and TLR4 receptors
por: Fernández-Arjona, María del Mar, et al.
Publicado: (2019)

Sudden cessation of fluoxetine before alcohol drinking reinstatement alters microglial morphology and TLR4/inflammatory neuroadaptation in the rat brain
por: Aranda, Jesús, et al.
Publicado: (2021)

Age related changes in microglial phenotype vary between CNS regions: Grey versus white matter differences
por: Hart, Adam D., et al.
Publicado: (2012)

Cardioprotective Antioxidant and Anti-Inflammatory Mechanisms Induced by Intermittent Hypobaric Hypoxia
por: González-Candia, Alejandro, et al.
Publicado: (2022)

Microglial responses around intrinsic CNS neurons are correlated with axonal regeneration
por: Shokouhi, Bahman N, et al.
Publicado: (2010)

GLP-1 secretion by microglial cells and decreased CNS expression in obesity
por: Kappe, Camilla, et al.
Publicado: (2012)

The TRAPs From Microglial Vesicles Protect Against Listeria Infection in the CNS
por: Wang, Chao, et al.
Publicado: (2019)

Evidence of Microglial Immune Response Following Coronavirus PHEV Infection of CNS
por: Zhang, Jing, et al.
Publicado: (2022)

Triticum vulgare extract exerts an anti-inflammatory action in two in vitro models of inflammation in microglial cells
por: Sanguigno, Luca, et al.
Publicado: (2018)

Blue Light Modulates Murine Microglial Gene Expression in the Absence of Optogenetic Protein Expression
por: Cheng, Kevin P., et al.
Publicado: (2016)

Deletion of Metallothionein Exacerbates Intermittent Hypoxia-Induced Oxidative and Inflammatory Injury in Aorta
por: Zhou, Shanshan, et al.
Publicado: (2014)

Lithium Chloride Exerts Anti-Inflammatory and Neuroprotective Effects by Inhibiting Microglial Activation in LPS-Induced Retinal Injury
por: Wu, Nandan, et al.
Publicado: (2023)

The Effects of Hypoxia and Inflammation on Synaptic Signaling in the CNS
por: Mukandala, Gatambwa, et al.
Publicado: (2016)

Inflammatory and oxidative stress-associated factors in chronic intermittent hypoxia in Chinese patients, rats, lymphocytes and endotheliocytes
por: Ren, Hui, et al.
Publicado: (2017)

Atractylon treatment prevents sleep-disordered breathing-induced cognitive dysfunction by suppression of chronic intermittent hypoxia-induced M1 microglial activation
por: Lin, Yan, et al.
Publicado: (2020)

Intrathecal antagonism of microglial TLR(4) reduces inflammatory damage to blood–spinal cord barrier following ischemia/reperfusion injury in rats
por: Li, Xiao-Qian, et al.
Publicado: (2014)

Hypobaric Intermittent Hypoxia Attenuates Hypoxia-induced Depressor Response
por: Cui, Fang, et al.
Publicado: (2012)

Mechanisms of intermittent hypoxia induced hypertension
por: Bosc, Laura V González, et al.
Publicado: (2010)

Intermittent hypoxia produces Alzheimer disease?
por: Yagishita, Sosuke, et al.
Publicado: (2017)

The Impact of Intermittent Hypoxia on Metabolism and Cognition
por: Shobatake, Ryogo, et al.
Publicado: (2022)

The Role of Intermittent Hypoxia on the Proliferative Inhibition of Rat Cerebellar Astrocytes
por: Chiu, Sheng-Chun, et al.
Publicado: (2015)

A New Device to Mimic Intermittent Hypoxia in Mice
por: Chodzyński, Kamil J., et al.
Publicado: (2013)

Chronic and intermittent hypoxia differentially regulate left ventricular inflammatory and extracellular matrix responses
por: Ramirez, Trevi A, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_bpdadm0hdncsrvstmh3s5kjkl5