Cargando…

Construction of an in vitro bypassed pyruvate decarboxylation pathway using thermostable enzyme modules and its application to N-acetylglutamate production

BACKGROUND: Metabolic engineering has emerged as a practical alternative to conventional chemical conversion particularly in biocommodity production processes. However, this approach is often hampered by as yet unidentified inherent mechanisms of natural metabolism. One of the possible solutions for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Krutsakorn, Borimas, Imagawa, Takashi, Honda, Kohsuke, Okano, Kenji, Ohtake, Hisao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852541/ https://www.ncbi.nlm.nih.gov/pubmed/24099461 http://dx.doi.org/10.1186/1475-2859-12-91

Ejemplares similares

Redirection of the Reaction Specificity of a Thermophilic Acetolactate Synthase toward Acetaldehyde Formation
por: Cheng, Maria, et al.
Publicado: (2016)

Decarboxylation of Pyruvate to Acetaldehyde for Ethanol Production by Hyperthermophiles
por: Eram, Mohammad S., et al.
Publicado: (2013)

Construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering
por: Lee, Kyoung Ho, et al.
Publicado: (2013)

Transcriptional Regulation of N-Acetylglutamate Synthase
por: Heibel, Sandra Kirsch, et al.
Publicado: (2012)

N-Acetylglutamate Synthase Deficiency Due to a Recurrent Sequence Variant in the N-acetylglutamate Synthase Enhancer Region
por: Williams, Monique, et al.
Publicado: (2018)

Synthetic metabolic engineering-a novel, simple technology for designing a chimeric metabolic pathway
por: Ye, Xiaoting, et al.
Publicado: (2012)

A novel bifunctional N-acetylglutamate synthase-kinase from Xanthomonas campestris that is closely related to mammalian N-acetylglutamate synthase
por: Qu, Qiuhao, et al.
Publicado: (2007)

Gene delivery corrects N-acetylglutamate synthase deficiency and enables insights in the physiological impact of L-arginine activation of N-acetylglutamate synthase
por: Sonaimuthu, P., et al.
Publicado: (2021)

The N-Acetylglutamate Synthase Family: Structures, Function and Mechanisms
por: Shi, Dashuang, et al.
Publicado: (2015)

Effect of arginine on oligomerization and stability of N-acetylglutamate synthase
por: Haskins, N., et al.
Publicado: (2016)

Expression Pattern and Biochemical Properties of Zebrafish N-Acetylglutamate Synthase
por: Caldovic, Ljubica, et al.
Publicado: (2014)

A Novel N-Acetylglutamate Synthase Architecture Revealed by the Crystal Structure of the Bifunctional Enzyme from Maricaulis maris
por: Shi, Dashuang, et al.
Publicado: (2011)

To beat the heat – engineering of the most thermostable pyruvate decarboxylase to date
por: Sutiono, Samuel, et al.
Publicado: (2019)

Modules for in vitro metabolic engineering: Pathway assembly for bio-based production of value-added chemicals
por: Taniguchi, Hironori, et al.
Publicado: (2017)

N-acetylglutamate synthase deficiency: an insight into the genetics, epidemiology, pathophysiology, and treatment
por: Mew, Nicholas Ah, et al.
Publicado: (2011)

Presentation and management of N-acetylglutamate synthase deficiency: a review of the literature
por: Kenneson, Aileen, et al.
Publicado: (2020)

Thermostable Artificial Enzyme Isolated by In Vitro Selection
por: Morelli, Aleardo, et al.
Publicado: (2014)

Characterization of thermostable serine hydroxymethyltransferase for β-hydroxy amino acids synthesis
por: Ma’ruf, Ilma Fauziah, et al.
Publicado: (2022)

A Reconstructed Common Ancestor of the Fatty Acid Photo‐decarboxylase Clade Shows Photo‐decarboxylation Activity and Increased Thermostability
por: Sun, Yue, et al.
Publicado: (2021)

Insight on an Arginine Synthesis Metabolon from the Tetrameric Structure of Yeast Acetylglutamate Kinase
por: de Cima, Sergio, et al.
Publicado: (2012)

N-acetylglutamic acid alleviates oxidative stress based on histone acetylation in plants
por: Hirakawa, Takeshi, et al.
Publicado: (2023)

Developing a single strain for in vitro salvage synthesis of NAD(+) at high temperatures and its potential for bioconversion
por: Taniguchi, Hironori, et al.
Publicado: (2019)

Decarboxylative Alkenylation
por: Edwards, Jacob T., et al.
Publicado: (2017)

Role of carglumic acid in the treatment of acute hyperammonemia due to N-acetylglutamate synthase deficiency
por: Häberle, Johannes
Publicado: (2011)

N‐acetylglutamate synthase deficiency with associated 3‐methylglutaconic aciduria: A case report
por: Selvanathan, Arthavan, et al.
Publicado: (2022)

ATF4 over-expression increased IgG(1) productivity in Chinese hamster ovary cells
por: Haredy, Ahmad M, et al.
Publicado: (2011)

Decarboxylative Triazolation Enables Direct Construction of Triazoles from Carboxylic Acids
por: Dang, Hang T., et al.
Publicado: (2023)

Phenotyping the quality of complex medium components by simple online-monitored shake flask experiments
por: Diederichs, Sylvia, et al.
Publicado: (2014)

Inversion of allosteric effect of arginine on N-acetylglutamate synthase, a molecular marker for evolution of tetrapods
por: Haskins, Nantaporn, et al.
Publicado: (2008)

Thermostable and O(2)-Insensitive Pyruvate Decarboxylases from Thermoacidophilic Archaea Catalyzing the Production of Acetaldehyde
por: Alharbi, Faisal, et al.
Publicado: (2022)

Simple technology for recycling phosphate from wastewater to farmland in rural areas
por: Ohtake, Hisao, et al.
Publicado: (2017)

Chromosome identification and its application in Chinese hamster ovary cells
por: Cao, Yihua, et al.
Publicado: (2011)

Decarboxylative trifluoromethylthiolation of pyridylacetates
por: Kawanishi, Ryouta, et al.
Publicado: (2021)

TEMPURA: Database of Growth TEMPeratures of Usual and RAre Prokaryotes
por: Sato, Yu, et al.
Publicado: (2020)

A novel type of N-acetylglutamate synthase is involved in the first step of arginine biosynthesis in Corynebacterium glutamicum
por: Petri, Kathrin, et al.
Publicado: (2013)

Lysinuric protein intolerance mimicking N-acetylglutamate synthase deficiency in a nine-year-old boy
por: Al-Qattan, Sarah, et al.
Publicado: (2021)

Generation of a Yeast Cell Model Potentially Useful to Identify the Mammalian Mitochondrial N-Acetylglutamate Transporter
por: Gorgoglione, Ruggiero, et al.
Publicado: (2023)

Potential and utilization of thermophiles and thermostable enzymes in biorefining
por: Turner, Pernilla, et al.
Publicado: (2007)

Review: Engineering of thermostable enzymes for industrial applications
por: Rigoldi, Federica, et al.
Publicado: (2018)

Characterization of the first naturally thermostable terpene synthases and development of strategies to improve thermostability in this family of enzymes
por: Styles, Matthew Q., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_pgf9h14v54sejan9kgm7l6956e