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The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinoma
BACKGROUND: Overexpression of Decoy Receptor 3 (DcR3), a soluble member of the tumor necrosis factor receptor superfamily, is a common event in several types of cancer. In renal cell carcinoma (RCC), DcR3 overexpression is associated with lymph node and distant metastasis as well as a poor prognosis...
Autores principales: | Weissinger, Daniel, Tagscherer, Katrin E, Macher-Göppinger, Stephan, Haferkamp, Axel, Wagener, Nina, Roth, Wilfried |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852559/ https://www.ncbi.nlm.nih.gov/pubmed/24107265 http://dx.doi.org/10.1186/1476-4598-12-120 |
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