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Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies

Electron paramagnetic resonance (EPR) and online UV–visible absorption microspectrophotometry with X-ray crystallography have been used in a complementary manner to follow X-ray-induced disulfide-bond cleavage. Online UV–visible spectroscopy showed that upon X-irradiation, disulfide radicalization a...

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Detalles Bibliográficos
Autores principales: Sutton, Kristin A., Black, Paul J., Mercer, Kermit R., Garman, Elspeth F., Owen, Robin L., Snell, Edward H., Bernhard, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852651/
https://www.ncbi.nlm.nih.gov/pubmed/24311579
http://dx.doi.org/10.1107/S0907444913022117

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