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Topical Promethazine Side Effects: Our Experience and Review of the Literature
Promethazine hydrochloride is a first-generation H1 receptor antagonist, antihistamine, and antiemetic medication that can also have strong sedative effects. The apparent ability of topical H1r/2r antagonists to target epidermal H1/2r was translated into increased efficacy in the treatment of inflam...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852816/ https://www.ncbi.nlm.nih.gov/pubmed/24350243 http://dx.doi.org/10.1155/2013/151509 |
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author | Cantisani, C. Ricci, S. Grieco, T. Paolino, G. Faina, V. Silvestri, E. Calvieri, S. |
author_facet | Cantisani, C. Ricci, S. Grieco, T. Paolino, G. Faina, V. Silvestri, E. Calvieri, S. |
author_sort | Cantisani, C. |
collection | PubMed |
description | Promethazine hydrochloride is a first-generation H1 receptor antagonist, antihistamine, and antiemetic medication that can also have strong sedative effects. The apparent ability of topical H1r/2r antagonists to target epidermal H1/2r was translated into increased efficacy in the treatment of inflammatory dermatoses, likely due to decreased inflammation and enhanced barrier function. |
format | Online Article Text |
id | pubmed-3852816 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-38528162013-12-12 Topical Promethazine Side Effects: Our Experience and Review of the Literature Cantisani, C. Ricci, S. Grieco, T. Paolino, G. Faina, V. Silvestri, E. Calvieri, S. Biomed Res Int Review Article Promethazine hydrochloride is a first-generation H1 receptor antagonist, antihistamine, and antiemetic medication that can also have strong sedative effects. The apparent ability of topical H1r/2r antagonists to target epidermal H1/2r was translated into increased efficacy in the treatment of inflammatory dermatoses, likely due to decreased inflammation and enhanced barrier function. Hindawi Publishing Corporation 2013 2013-11-19 /pmc/articles/PMC3852816/ /pubmed/24350243 http://dx.doi.org/10.1155/2013/151509 Text en Copyright © 2013 C. Cantisani et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Cantisani, C. Ricci, S. Grieco, T. Paolino, G. Faina, V. Silvestri, E. Calvieri, S. Topical Promethazine Side Effects: Our Experience and Review of the Literature |
title | Topical Promethazine Side Effects: Our Experience and Review of the Literature |
title_full | Topical Promethazine Side Effects: Our Experience and Review of the Literature |
title_fullStr | Topical Promethazine Side Effects: Our Experience and Review of the Literature |
title_full_unstemmed | Topical Promethazine Side Effects: Our Experience and Review of the Literature |
title_short | Topical Promethazine Side Effects: Our Experience and Review of the Literature |
title_sort | topical promethazine side effects: our experience and review of the literature |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852816/ https://www.ncbi.nlm.nih.gov/pubmed/24350243 http://dx.doi.org/10.1155/2013/151509 |
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