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Topical Promethazine Side Effects: Our Experience and Review of the Literature

Promethazine hydrochloride is a first-generation H1 receptor antagonist, antihistamine, and antiemetic medication that can also have strong sedative effects. The apparent ability of topical H1r/2r antagonists to target epidermal H1/2r was translated into increased efficacy in the treatment of inflam...

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Detalles Bibliográficos
Autores principales: Cantisani, C., Ricci, S., Grieco, T., Paolino, G., Faina, V., Silvestri, E., Calvieri, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852816/
https://www.ncbi.nlm.nih.gov/pubmed/24350243
http://dx.doi.org/10.1155/2013/151509
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author Cantisani, C.
Ricci, S.
Grieco, T.
Paolino, G.
Faina, V.
Silvestri, E.
Calvieri, S.
author_facet Cantisani, C.
Ricci, S.
Grieco, T.
Paolino, G.
Faina, V.
Silvestri, E.
Calvieri, S.
author_sort Cantisani, C.
collection PubMed
description Promethazine hydrochloride is a first-generation H1 receptor antagonist, antihistamine, and antiemetic medication that can also have strong sedative effects. The apparent ability of topical H1r/2r antagonists to target epidermal H1/2r was translated into increased efficacy in the treatment of inflammatory dermatoses, likely due to decreased inflammation and enhanced barrier function.
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spelling pubmed-38528162013-12-12 Topical Promethazine Side Effects: Our Experience and Review of the Literature Cantisani, C. Ricci, S. Grieco, T. Paolino, G. Faina, V. Silvestri, E. Calvieri, S. Biomed Res Int Review Article Promethazine hydrochloride is a first-generation H1 receptor antagonist, antihistamine, and antiemetic medication that can also have strong sedative effects. The apparent ability of topical H1r/2r antagonists to target epidermal H1/2r was translated into increased efficacy in the treatment of inflammatory dermatoses, likely due to decreased inflammation and enhanced barrier function. Hindawi Publishing Corporation 2013 2013-11-19 /pmc/articles/PMC3852816/ /pubmed/24350243 http://dx.doi.org/10.1155/2013/151509 Text en Copyright © 2013 C. Cantisani et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Cantisani, C.
Ricci, S.
Grieco, T.
Paolino, G.
Faina, V.
Silvestri, E.
Calvieri, S.
Topical Promethazine Side Effects: Our Experience and Review of the Literature
title Topical Promethazine Side Effects: Our Experience and Review of the Literature
title_full Topical Promethazine Side Effects: Our Experience and Review of the Literature
title_fullStr Topical Promethazine Side Effects: Our Experience and Review of the Literature
title_full_unstemmed Topical Promethazine Side Effects: Our Experience and Review of the Literature
title_short Topical Promethazine Side Effects: Our Experience and Review of the Literature
title_sort topical promethazine side effects: our experience and review of the literature
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852816/
https://www.ncbi.nlm.nih.gov/pubmed/24350243
http://dx.doi.org/10.1155/2013/151509
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