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Synthesis, characterization, and evaluation of a novel inhibitor of WNT/β-catenin signaling pathway
BACKGROUND: Wnt/β-catenin signaling is a highly conserved pathway in organism evolution and is important in many biological processes. Overactivation of Wnt/β-catenin signaling is closely related to tumor development and progression. To identify potent small molecules that can fight aberrant Wnt/β-c...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852836/ https://www.ncbi.nlm.nih.gov/pubmed/24098916 http://dx.doi.org/10.1186/1476-4598-12-116 |